Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12646370 | 0.83 | GAA (0.46) | GAASLC22A1CYP3A4CYP2D6TSHR | |
| SCHEMBL6123801 | 0.83 | GAA (0.46) | GAASLC22A1CYP3A4CYP2D6TSHR | |
| SCHEMBL10033223 | 0.83 | GAA (0.46) | GAASLC22A1CYP3A4CYP2D6TSHR | |
| SCHEMBL4122808 | 0.82 | GAA (0.46) | GAACYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL13301282 | 0.82 | GAA (0.46) | GAACYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL12960706 | 0.81 | GAA (0.47) | GAASLC22A1CYP3A4CYP2D6TSHR | |
| SCHEMBL12006858 | 0.81 | GAA (0.47) | GAASLC22A1CYP3A4CYP2D6TSHR | |
| SCHEMBL4127868 | 0.81 | GAA (0.47) | GAASLC22A1CYP3A4CYP2D6TSHR | |
| SCHEMBL12013632 | 0.81 | GAA (0.47) | GAASLC22A1CYP3A4CYP2D6TSHR | |
| SCHEMBL11497217 | 0.80 | OPRM1 (0.35) | GAASLC22A1CYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367827-B2 | Process for preparing hydrocodone using a super acid | MALLINCKRODT LLC (US) | 2013-02-05 | — | — | US | disclosed |
| US-20100137598-A1 | Process for Preparing Hydrocodone Using a Super Acid | MALLINCKRODT INC. (US) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137598-A1 | Process for Preparing Hydrocodone Using a Super Acid | HAAO, CYP7A1, CYP3A5 | GAA 1908/4885SLC22A1 3095/4885CYP3A4 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.