Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928052 | 0.96 | KDM4E (0.53) | KDM4EL3MBTL1ATMGAAGFER | |
| SCHEMBL8928071 | 0.96 | KDM4E (0.53) | KDM4EL3MBTL1ATMGAAGFER | |
| SCHEMBL8928058 | 0.96 | KDM4E (0.53) | KDM4EL3MBTL1ATMGAAGFER | |
| SCHEMBL14119152 | 0.96 | KDM4E (0.53) | KDM4EL3MBTL1ATMGAAGFER | |
| SCHEMBL12117329 | 0.95 | KDM4E (0.49) | KDM4EL3MBTL1ATMGAAGFER | |
| SCHEMBL15480788 | 0.94 | KDM4E (0.47) | KDM4EL3MBTL1ATMGAAGFER | |
| SCHEMBL15747059 | 0.94 | KDM4E (0.51) | KDM4EL3MBTL1ATMGAAGFER | |
| SCHEMBL15747065 | 0.94 | KDM4E (0.47) | KDM4EL3MBTL1ATMGAAGFER | |
| SCHEMBL3333309 | 0.94 | KDM4E (0.51) | KDM4EL3MBTL1ATMGAAGFER | |
| SCHEMBL13725850 | 0.92 | KDM4E (0.49) | KDM4EL3MBTL1ATMGAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100145067-A1 | NOVEL CARBAZOLES DERIVATIVE AND USE THEREOF | BANDO CHEMICAL INDUSTRIES, LTD. (JP) | 2010-06-10 | — | — | US | disclosed |
| US-20100145067-A1 | NOVEL CARBAZOLES DERIVATIVE AND USE THEREOF | BANDO CHEMICAL INDUSTRIES, LTD. (JP) | 2010-06-10 | — | — | US | disclosed |
| EP-2100880-A1 | NOVEL CARBAZOLE DERIVATIVE AND USE THEREOF | Bando Chemical Industries, Ltd. (JP) | 2009-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145067-A1 | NOVEL CARBAZOLES DERIVATIVE AND USE THEREOF | GDI2, SGK2, GDI1 | KDM4E 1016/4885L3MBTL1 3298/4885ATM 1735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.