Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.57 |
| ▸ | GPBAR1 | Q8TDU6 | 11/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NT5E | P21589 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | F3 | P13726 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | GLI1 | P08151 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.51 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13301993 | 0.90 | SLC10A1 (0.70) | SLC10A1GPBAR1LMNANT5ESMN1; SMN2 | |
| SCHEMBL13301992 | 0.90 | SLC10A1 (0.64) | SLC10A1GPBAR1LMNANT5ESMN1; SMN2 | |
| SCHEMBL13293257 | 0.88 | GPBAR1 (0.69) | SLC10A1GPBAR1LMNANT5ESMN1; SMN2 | |
| SCHEMBL16705031 | 0.84 | F3 (0.71) | SLC10A1GPBAR1LMNANT5EF3 | |
| SCHEMBL3506340 | 0.84 | GPBAR1 (0.75) | GPBAR1LMNANT5ESMN1; SMN2F3 | |
| SCHEMBL13301931 | 0.83 | PTGES (0.61) | SLC10A1GPBAR1LMNANT5ESMN1; SMN2 | |
| SCHEMBL13293256 | 0.82 | GPBAR1 (0.67) | GPBAR1LMNANT5ESMN1; SMN2F3 | |
| SCHEMBL13293148 | 0.81 | SLC10A1 (0.71) | SLC10A1GPBAR1LMNANT5ESMN1; SMN2 | |
| SCHEMBL13910823 | 0.81 | GPBAR1 (0.81) | GPBAR1LMNANT5ESMN1; SMN2F3 | |
| SCHEMBL13293261 | 0.80 | GPBAR1 (0.59) | GPBAR1LMNANT5ESMN1; SMN2F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068668-A1 | 23-SUBSTITUTED DERIVATIVES OF LUPANE-TYPE PENTACYCLIC TRITERPENOIDS | ADVANCED LIFE SCIENCES, INC. (US) | 2010-06-17 | — | — | WO | disclosed |