Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.64 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NT5E | P21589 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13301993 | 0.96 | SLC10A1 (0.70) | SLC10A1PTGESLMNANT5EUSP2 | |
| SCHEMBL13301931 | 0.94 | PTGES (0.61) | SLC10A1PTGESLMNANT5EUSP2 | |
| SCHEMBL13301976 | 0.90 | SLC10A1 (0.57) | SLC10A1LMNANT5EUSP2HIF1A | |
| SCHEMBL13293212 | 0.88 | SLC10A1 (0.61) | SLC10A1PTGESLMNANT5EUSP2 | |
| SCHEMBL13293148 | 0.87 | SLC10A1 (0.71) | SLC10A1PTGESLMNANT5EUSP2 | |
| SCHEMBL13304150 | 0.86 | SLC10A1 (0.70) | SLC10A1PTGESLMNANT5EUSP2 | |
| SCHEMBL13293259 | 0.84 | PTGES (0.62) | SLC10A1PTGESLMNANT5EUSP2 | |
| SCHEMBL13304147 | 0.84 | SLC10A1 (0.67) | SLC10A1PTGESLMNANT5EUSP2 | |
| SCHEMBL13293222 | 0.83 | SLC10A1 (0.66) | SLC10A1PTGESLMNANT5EUSP2 | |
| SCHEMBL13910776 | 0.83 | SLC10A1 (0.72) | SLC10A1PTGESLMNANT5EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068668-A1 | 23-SUBSTITUTED DERIVATIVES OF LUPANE-TYPE PENTACYCLIC TRITERPENOIDS | ADVANCED LIFE SCIENCES, INC. (US) | 2010-06-17 | — | — | WO | disclosed |