Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.35 |
| ▸ | EBP | Q15125 | 1/20 | 0.35 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3337535 | 0.92 | EBP (0.38) | CYP19A1ALDH1A1SMN1; SMN2BDKRB1EBP | |
| Hydrochloric Acid SCHEMBL640337 | 0.91 | EBP (0.37) | ALDH1A1BDKRB1EBPDHCR7HTR7 | |
| SCHEMBL10205618 | 0.91 | EBP (0.44) | TSHRNPSR1ALDH1A1EBPDHCR7 | |
| Hydrochloric Acid SCHEMBL640696 | 0.90 | EBP (0.43) | TSHRNPSR1ALDH1A1EBPDHCR7 | |
| SCHEMBL10205617 | 0.89 | EPHX2 (0.39) | TSHRNPSR1CYP19A1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL640205 | 0.88 | EPHX2 (0.39) | TSHRNPSR1CYP19A1ALDH1A1LMNA | |
| SCHEMBL640785 | 0.83 | EPHX2 (0.40) | TSHRNPSR1CYP19A1ALDH1A1LMNA | |
| SCHEMBL640174 | 0.82 | EBP (0.52) | NPSR1ALDH1A1EBPDHCR7EPHX2 | |
| Hydrochloric Acid SCHEMBL639042 | 0.82 | EPHX2 (0.40) | TSHRNPSR1CYP19A1ALDH1A1LMNA | |
| SCHEMBL639078 | 0.81 | EBP (0.48) | NPSR1ALDH1A1EBPDHCR7EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152158-A1 | Substituted Disulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| US-20100152158-A1 | Substituted Disulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152158-A1 | Substituted Disulfonamide Compounds | BDKRB1, BDKRB2, BRS3 | TSHR 287/4885NPSR1 4/4885CYP19A1 2236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.