Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 5/20 | 0.52 |
| ▸ | DHCR7 | Q9UBM7 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10205618 | 0.92 | EBP (0.44) | EBPDHCR7ALDH1A1NPSR1EPHX2 | |
| Hydrochloric Acid SCHEMBL640696 | 0.91 | EBP (0.43) | EBPDHCR7ALDH1A1NPSR1EPHX2 | |
| SCHEMBL10205615 | 0.89 | EBP (0.42) | EBPDHCR7ALDH1A1NPSR1EPHX2 | |
| SCHEMBL639078 | 0.88 | EBP (0.48) | EBPDHCR7ALDH1A1NPSR1EPHX2 | |
| Hydrochloric Acid SCHEMBL640548 | 0.88 | EBP (0.42) | EBPDHCR7ALDH1A1NPSR1EPHX2 | |
| Hydrochloric Acid SCHEMBL640549 | 0.88 | EBP (0.42) | EBPDHCR7ALDH1A1NPSR1EPHX2 | |
| SCHEMBL639404 | 0.85 | HTR7 (0.43) | EBPDHCR7ALDH1A1NPSR1EPHX2 | |
| SCHEMBL13302192 | 0.82 | TSHR (0.37) | EBPDHCR7ALDH1A1NPSR1EPHX2 | |
| SCHEMBL640570 | 0.82 | EBP (0.58) | EBPDHCR7ALDH1A1NPSR1EPHX2 | |
| SCHEMBL22081215 | 0.81 | EBP (0.64) | EBPDHCR7ALDH1A1NPSR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119805-B2 | Substituted disulfonamide compounds | GRUENENTHAL GMBH (DE) | 2012-02-21 | — | — | US | claimed |
| US-20100152158-A1 | Substituted Disulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2010-06-17 | — | — | US | claimed |
| US-8119805-B2 | Substituted disulfonamide compounds | GRUENENTHAL GMBH (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119805-B2 | Substituted disulfonamide compounds | GRUENENTHAL GMBH (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119805-B2 | Substituted disulfonamide compounds | GRUENENTHAL GMBH (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20100152158-A1 | Substituted Disulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| US-20100152158-A1 | Substituted Disulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| US-20100152158-A1 | Substituted Disulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152158-A1 | Substituted Disulfonamide Compounds | BDKRB1, BDKRB2, BRS3 | EBP 2904/4885DHCR7 1725/4885ALDH1A1 1278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.