Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 6/20 | 0.40 |
| ▸ | GSK3B | P49841 | 14/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14411150 | 0.83 | CDK2 (0.60) | CDK2GSK3BCCNE1 | |
| SCHEMBL12952928 | 0.83 | CDK2 (0.60) | CDK2GSK3BCCNE1 | |
| SCHEMBL12952863 | 0.73 | GSK3B (0.47) | CDK2GSK3BCCNE1 | |
| SCHEMBL12954271 | 0.71 | CDK2 (0.57) | CDK2GSK3BCCNE1 | |
| SCHEMBL14050841 | 0.69 | GSK3B (0.49) | CDK2GSK3BCCNE1 | |
| SCHEMBL13305417 | 0.68 | GSK3B (0.46) | CDK2GSK3BCCNE1 | |
| SCHEMBL14545780 | 0.68 | CDK2 (0.60) | CDK2GSK3BCCNE1 | |
| SCHEMBL14582509 | 0.68 | CDK2 (0.59) | CDK2GSK3BCCNE1 | |
| SCHEMBL14545782 | 0.67 | GSK3B (0.47) | CDK2GSK3BCCNE1 | |
| SCHEMBL13305361 | 0.67 | GSK3B (0.49) | CDK2GSK3BCCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537116-B1 | PYRAZOLOPYRIMIDINES SUITABLE FOR THE TREATMENT OF CANCER DISEASES | SCHERING CORP (US) | 2010-06-02 | — | — | EP | disclosed |