Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 13/20 | 0.47 |
| ▸ | CDK2 | P24941 | 8/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12953681 | 0.80 | GSK3B (0.73) | GSK3BCDK2CCNE1 | |
| SCHEMBL14050841 | 0.74 | GSK3B (0.49) | GSK3BCDK2CCNE1 | |
| SCHEMBL13116859 | 0.71 | GSK3B (0.77) | GSK3BCDK2CCNE1 | |
| SCHEMBL17690923 | 0.71 | GSK3B (0.48) | GSK3BCDK2CCNE1 | |
| SCHEMBL13305318 | 0.70 | GSK3B (0.50) | GSK3BCDK2 | |
| SCHEMBL13305417 | 0.70 | GSK3B (0.46) | GSK3BCDK2CCNE1 | |
| SCHEMBL13304885 | 0.69 | GSK3B (0.65) | GSK3BCDK2CCNE1 | |
| SCHEMBL13146313 | 0.69 | GSK3B (0.57) | GSK3BCDK2CCNE1 | |
| SCHEMBL14545227 | 0.69 | GSK3B (0.45) | GSK3BCDK2CCNE1 | |
| SCHEMBL13304685 | 0.67 | CDK2 (0.40) | GSK3BCDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044449-A2 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |