Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18381453 | 0.88 | NPC1 (0.57) | NPC1MAPTGFERRAB9AMEN1 | |
| SCHEMBL30872347 | 0.84 | NPC1 (0.53) | NPC1MAPTGFERRAB9AMEN1 | |
| SCHEMBL10892919 | 0.82 | CYP19A1 (0.62) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL1099649 | 0.82 | MAPT (0.61) | NPC1MAPTGFERRAB9AMEN1 | |
| SCHEMBL10892923 | 0.82 | CYP19A1 (0.62) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL1099648 | 0.82 | MAPT (0.61) | NPC1MAPTGFERRAB9AMEN1 | |
| SCHEMBL13304744 | 0.81 | RELA (0.70) | NPC1MAPTGFERRAB9AMEN1 | |
| SCHEMBL29966849 | 0.81 | RELA (0.70) | NPC1MAPTGFERRAB9AMEN1 | |
| SCHEMBL28889113 | 0.81 | RELA (0.70) | NPC1MAPTGFERRAB9AMEN1 | |
| SCHEMBL3163586 | 0.81 | RELA (0.70) | NPC1MAPTGFERRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8829783-B2 | Trinaphthyl monoamine or derivative thereof, organic electroluminescent device using the same, and organic electroluminescent material-containing solution | IDEMITSU KOSAN CO., LTD. (JP) | 2014-09-09 | — | — | US | disclosed |
| US-20100156285-A1 | TRINAPHTHYL MONOAMINE OR DERIVATIVE THEREOF, ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME, AND ORGANIC ELECTROLUMINESCENT MATERIAL-CONTAINING SOLUTION | IDEMITSU KOSAN CO., LTD. (JP) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100156285-A1 | TRINAPHTHYL MONOAMINE OR DERIVATIVE THEREOF, ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME, AND ORGANIC ELECTROLUMINESCENT MATERIAL-CONTAINING SOLUTION | MAOA, COMT, MAOB | NPC1 4787/4885MAPT 194/4885GFER 1706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.