SCHEMBL13305286

SCHEMBL13305286

FC(F)(F)c1ccc2c(c1)N(CCCN1CCCCC1)c1ccccc1S2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 11/20 1.00
LMNA P02545 6/20 0.81
MAPT P10636 6/20 0.81
SMN1; SMN2 Q16637 5/20 0.81
CYP3A4 P08684 4/20 0.81
MAPK1 P28482 4/20 0.81
TP53 P04637 3/20 0.81
DRD2 P14416 3/20 0.81
DRD1 P21728 3/20 0.81
HRH1 P35367 3/20 0.81
DRD3 P35462 3/20 0.81
RAD52 P43351 3/20 0.81
ALDH1A1 P00352 2/20 0.81
CYP1A2 P05177 2/20 0.81
ABCB1 P08183 2/20 0.81
HTR1A P08908 2/20 0.81
ADRA2A P08913 2/20 0.81
ADORA3 P0DMS8 2/20 0.81
CYP2D6 P10635 2/20 0.81
CHRM1 P11229 2/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23353452 0.99 FPR2 (0.98) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL23353451 0.98 FPR2 (0.96) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL21445255 0.98 FPR2 (1.00) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL23353449 0.98 FPR2 (0.95) FPR2LMNAMAPTSMN1; SMN2CYP3A4
Hydrochloric Acid SCHEMBL11514840 0.98 FPR2 (0.95) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL23353455 0.97 FPR2 (0.93) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL4279887 0.92 FPR2 (0.84) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL26001737 0.91 FPR2 (0.83) FPR2LMNAMAPTSMN1; SMN2CYP3A4
Homofenazine SCHEMBL1643422 0.90 LMNA (0.94) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL9086491 0.90 FPR2 (0.82) FPR2LMNAMAPTSMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250034193-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF CAMP4 THERAPEUTICS CORPORATION 2025-01-30 US disclosed
US-12145963-B2 Phenothiazine derivatives and uses thereof CAMP4 THERAPEUTICS CORPORATION (US) 2024-11-19 US disclosed
US-20230257410-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF CAMP4 THERAPEUTICS CORPORATION 2023-08-17 US disclosed
US-20230257410-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF CAMP4 THERAPEUTICS CORPORATION 2023-08-17 US disclosed
US-11542290-B2 Phenothiazine derivatives and uses thereof CAMP4 THERAPEUTICS CORPORATION (US) 2023-01-03 US disclosed
US-11542290-B2 Phenothiazine derivatives and uses thereof CAMP4 THERAPEUTICS CORPORATION (US) 2023-01-03 US disclosed
US-20210061837-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF CAMP4 THERAPEUTICS CORPORATION 2021-03-04 US disclosed
US-20210061837-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF CAMP4 THERAPEUTICS CORPORATION 2021-03-04 US disclosed
US-9012217-B2 Benzimidazole compounds differentiate a mammalian stem cell into mesodermal or cardiomyocyte cells BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) 2015-04-21 US disclosed
US-9012217-B2 Benzimidazole compounds differentiate a mammalian stem cell into mesodermal or cardiomyocyte cells BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) 2015-04-21 US disclosed
US-20100159596-A1 SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) 2010-06-24 US disclosed
US-20100159596-A1 SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) 2010-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210061837-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF RPLP2, RPS2, RPLP1 FPR2 2716/4885LMNA 546/4885MAPT 651/4885
US-20230257410-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF RPLP2, RPS2, RPLP1 FPR2 2716/4885LMNA 546/4885MAPT 651/4885
US-12145963-B2 Phenothiazine derivatives and uses thereof RPLP2, RPS2, RPLP1 FPR2 2716/4885LMNA 546/4885MAPT 651/4885
US-20100159596-A1 SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION RCOR3, BRD3, BRPF3 FPR2 4483/4885LMNA 2472/4885MAPT 4666/4885
US-20250034193-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF RPLP2, RPS2, RPLP1 FPR2 2716/4885LMNA 546/4885MAPT 651/4885
US-11542290-B2 Phenothiazine derivatives and uses thereof RPLP2, RPS2, RPLP1 FPR2 2716/4885LMNA 546/4885MAPT 651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.