Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.57 |
| ▸ | TLR2 | O60603 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20061869 | 0.87 | PRCP (0.57) | PRCPTLR2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL9044288 | 0.80 | PRCP (0.80) | PRCPTLR2 | |
| SCHEMBL8602848 | 0.80 | PRCP (0.80) | PRCPTLR2 | |
| SCHEMBL18631769 | 0.79 | PRCP (0.74) | PRCPTLR2 | |
| SCHEMBL18631778 | 0.79 | PRCP (0.74) | PRCPTLR2 | |
| SCHEMBL3231149 | 0.79 | PRCP (0.88) | PRCPTLR2 | |
| SCHEMBL13708495 | 0.79 | PRCP (0.56) | PRCPTLR2TSHRCYP3A4MAPT | |
| SCHEMBL26716600 | 0.79 | PRCP (0.56) | PRCPTLR2ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL18412267 | 0.78 | PRCP (0.53) | PRCPTLR2 | |
| Hydrochloric Acid SCHEMBL29619718 | 0.77 | PRCP (0.52) | PRCPTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497273-B1 | HYDROXAMIC ACID DERIVATIVES | NOVARTIS AG (CH) | 2010-06-09 | — | — | EP | disclosed |
| US-7589091-B2 | 2(R)-Benzyloxymethyl-4-[4-(4-chloro-phenyl)-piperazin-1-yl]-N-hydroxy-3(S)-(4-methoxy-phenyl)-4-oxo-butyramide; inhibiting matrix metalloproteinase; immunosuppression; neuropathic pain | NOVARTIS AG (CH) | 2009-09-15 | — | — | US | disclosed |
| US-7589091-B2 | 2(R)-Benzyloxymethyl-4-[4-(4-chloro-phenyl)-piperazin-1-yl]-N-hydroxy-3(S)-(4-methoxy-phenyl)-4-oxo-butyramide; inhibiting matrix metalloproteinase; immunosuppression; neuropathic pain | NOVARTIS AG (CH) | 2009-09-15 | — | — | US | disclosed |