Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24435974 | 0.79 | HDAC8 (0.38) | HDAC8PARP1KEAP1EGLN1 | |
| SCHEMBL24942541 | 0.77 | — | — | |
| SCHEMBL934894 | 0.77 | — | — | |
| SCHEMBL24958838 | 0.77 | — | — | |
| SCHEMBL1262340 | 0.77 | — | — | |
| SCHEMBL5200955 | 0.77 | — | — | |
| SCHEMBL24942714 | 0.75 | NPC1 (0.36) | KEAP1 | |
| SCHEMBL22130156 | 0.75 | NPC1 (0.34) | HDAC8KEAP1 | |
| SCHEMBL17970841 | 0.73 | HDAC8 (0.34) | HDAC8 | |
| SCHEMBL3688402 | 0.71 | TUBB4A (0.36) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9406943-B2 | Electrocatalysts using porous polymers and method of preparation | UCHICAGO ARGONNE, LLC (US) | 2016-08-02 | — | — | US | disclosed |
| US-20150194681-A1 | ELECTROCATALYSTS USING POROUS POLYMERS AND METHOD OF PREPARATION | UCHICAGO ARGONNE, LLC (US) | 2015-07-09 | — | — | US | disclosed |
| US-9012344-B2 | Electrocatalysts using porous polymers and method of preparation | UCHICAGO ARGONNE, LLC (US) | 2015-04-21 | — | — | US | disclosed |
| US-20110281719-A1 | ELECTROCATALYSTS USING POROUS POLYMERS AND METHOD OF PREPARATION | UCHICAGO ARGONNE, LLC | 2011-11-17 | — | — | US | disclosed |