⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL317020 | 0.89 | — | — | |
| SCHEMBL457301 | 0.89 | — | — | |
| SCHEMBL18037054 | 0.88 | ESR1 (0.31) | — | |
| SCHEMBL5542797 | 0.87 | CTSL (0.39) | — | |
| SCHEMBL5544544 | 0.87 | CTSL (0.39) | — | |
| SCHEMBL826778 | 0.87 | CTSL (0.39) | — | |
| SCHEMBL5253989 | 0.83 | TDP1 (0.38) | — | |
| SCHEMBL15689799 | 0.83 | ACACB (0.30) | — | |
| SCHEMBL1819553 | 0.79 | NCF1 (0.45) | — | |
| SCHEMBL5255428 | 0.76 | SMN1; SMN2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1776 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018021-B2 | Thiophene derivatives for the treatment of disorders caused by IgE | UCB Biopharma SRL (BE) | 2024-06-25 | — | — | US | claimed |
| WO-2024068520-A1 | 3-(HETERO)ARYL-5-CHLORODIFLUOROMETHYL-1,2,4-OXADIAZOLE AS FUNGICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 2024-04-04 | — | — | WO | claimed |
| WO-2024068519-A1 | 3-(HETERO)ARYL-5-CHLORODIFLUOROMETHYL-1,2,4-OXADIAZOLE AS FUNGICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 2024-04-04 | — | — | WO | claimed |
| EP-2788353-B1 | CAGE AMINE LIGANDS FOR METALLO-RADIOPHARMACEUTICALS | Clarity Pharmaceuticals Ltd (AU) | 2022-05-18 | — | — | EP | claimed |
| EP-3810606-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2021-04-28 | — | — | EP | claimed |
| CN-112566910-A | Thiophene derivatives for the treatment of IgE induced diseases | UCB生物制药有限责任公司 | 2021-03-26 | — | — | CN | claimed |
| WO-2019243550-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2019-12-26 | — | — | WO | claimed |
| EP-2758051-B1 | CYANOMETHYLPYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-04-11 | — | — | EP | claimed |
| US-9790202-B2 | Anthranilamide derivatives as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-10-17 | — | — | US | claimed |
| EP-2758389-B1 | PYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2017-06-07 | — | — | EP | claimed |
| EP-0848701-A1 | O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE IN CROP PROTECTION COMPOSITIONS | Novartis AG (CH) | 1998-06-24 | — | — | EP | claimed |
| EP-0836595-A1 | TRIAZOLINE AND ISOXAZOLINE BIS-OXIME DERIVATIVES AND THEIR USE AS PESTICIDES | Novartis AG (CH) | 1998-04-22 | — | — | EP | claimed |
| WO-1997002255-A1 | TRIAZOLINE AND ISOXAZOLINE BIS-OXIME DERIVATIVES AND THEIR USE AS PESTICIDES | NOVARTIS AG (CH) | 1997-01-23 | — | — | WO | claimed |
| WO-1997001530-A1 | O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE IN CROP PROTECTION COMPOSITIONS | NOVARTIS AG (CH) | 1997-01-16 | — | — | WO | claimed |
| EP-0742202-A2 | Benzophenone hydrazone derivatives as insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1996-11-13 | — | — | EP | claimed |
| US-5045108-A | Herbicidal and plant growth-regulating N-aryl-pyrrol-L-one and isoindol-2-one compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | claimed |
| US-4826993-A | Substituted diazolidinones | ELI LILLY AND COMPANY (US) | 1989-05-02 | — | — | US | claimed |
| US-4269773-A | CEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1981-05-26 | — | — | US | claimed |
| US-4205183-A | Facile method for isolating resolved amino acids | BECKMAN INSTRUMENTS, INC. (US) | 1980-05-27 | — | — | US | claimed |
| US-4180571-A | Arylmalonamido-1-oxadethiacephalosporins | SHIONOGI & CO., LTD. (JP) | 1979-12-25 | — | — | US | claimed |