Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 5/20 | 0.50 |
| ▸ | NOS1 | P29475 | 5/20 | 0.50 |
| ▸ | NOS3 | P29474 | 4/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104888 | 0.87 | NOS2 (0.65) | NOS2NOS1NOS3GRIN1GRIN2B | |
| SCHEMBL9880047 | 0.84 | MIF (0.53) | NOS3TAAR1GRIN2BSMN1; SMN2ALDH1A1 | |
| SCHEMBL23868267 | 0.81 | NOS2 (0.38) | NOS2NOS1NOS3GRIN1GRIN2B | |
| SCHEMBL1737052 | 0.71 | GRIN1 (0.62) | NOS2NOS1NOS3TAAR1GRIN1 | |
| SCHEMBL22068858 | 0.70 | NOS2 (0.65) | NOS2NOS1NOS3GRIN1GRIN2B | |
| SCHEMBL22068857 | 0.70 | NOS2 (0.65) | NOS2NOS1NOS3GRIN1GRIN2B | |
| SCHEMBL20675953 | 0.67 | NOS2 (0.96) | NOS2NOS1NOS3GRIN1GRIN2B | |
| SCHEMBL6191953 | 0.67 | NOS2 (0.61) | NOS2NOS1NOS3GRIN1GRIN2B | |
| SCHEMBL14291059 | 0.67 | NOS2 (0.96) | NOS2NOS1NOS3GRIN1GRIN2B | |
| SCHEMBL4097844 | 0.67 | GRIN2D (0.52) | NOS2NOS1NOS3TAAR1GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152407-A1 | NOVEL COMPOUNDS | LOCTITE (R&D) LIMITED (IE) | 2010-06-17 | — | — | US | disclosed |
| US-20100152407-A1 | NOVEL COMPOUNDS | LOCTITE (R&D) LIMITED (IE) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152407-A1 | NOVEL COMPOUNDS | KDM5B, KDM5C, KDM7A | NOS2 149/4885NOS1 188/4885NOS3 267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.