Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.39 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.39 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15434858 | 1.00 | CTSS (0.39) | CTSSCTSKCTSBCTSLPPARA | |
| SCHEMBL10192145 | 0.88 | KIF11 (0.41) | CTSSCTSKCTSBCTSLMAP1LC3B | |
| SCHEMBL13309372 | 0.88 | KIF11 (0.41) | CTSSCTSKCTSBCTSLMAP1LC3B | |
| SCHEMBL11920178 | 0.88 | KIF11 (0.45) | PPARAMAP1LC3BMAP1LC3AKIF11KCNH2 | |
| SCHEMBL10192147 | 0.87 | KIF11 (0.50) | CTSLPPARAMAP1LC3BMAP1LC3AKIF11 | |
| SCHEMBL13309006 | 0.87 | KIF11 (0.50) | CTSLPPARAMAP1LC3BMAP1LC3AKIF11 | |
| SCHEMBL10192157 | 0.87 | PPARG (0.47) | CTSSCTSKPPARAMAP1LC3BMAP1LC3A | |
| SCHEMBL10192174 | 0.86 | CYP19A1 (0.45) | PPARAPPARGLMNAPTGESKDM4E | |
| SCHEMBL10192158 | 0.85 | PPARA (0.39) | PPARAMAP1LC3BMAP1LC3AKIF11KCNH2 | |
| SCHEMBL3269903 | 0.78 | KIF11 (0.45) | KIF11KCNH2KDM4ENPSR1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511734-B1 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2010-06-23 | — | — | EP | disclosed |