Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3082391 | 0.89 | AR (0.46) | L3MBTL1EGLN2ARALDH1A1LMNA | |
| SCHEMBL13308554 | 0.83 | AR (0.35) | EGLN2ARALDH1A1KMT2ACYP11B1 | |
| SCHEMBL13308568 | 0.81 | RAB9A (0.41) | ALDH1A1LMNAMEN1KMT2AHTT | |
| SCHEMBL13308386 | 0.81 | AKR1B1 (0.37) | EGLN2ARCNR1S1PR1BRD4 | |
| SCHEMBL13308619 | 0.80 | POLB (0.45) | EGLN2ARLMNANPC1TSHR | |
| SCHEMBL13308563 | 0.79 | EGLN2 (0.39) | L3MBTL1EGLN2ARALDH1A1LMNA | |
| SCHEMBL13308976 | 0.78 | CNR1 (0.34) | EGLN2ARCYP11B1CYP11B2CNR1 | |
| SCHEMBL13309040 | 0.78 | EGLN2 (0.38) | EGLN2ARCYP11B1CYP11B2CNR1 | |
| SCHEMBL3070089 | 0.77 | AR (0.41) | L3MBTL1ARALDH1A1LMNAHTT | |
| SCHEMBL13308529 | 0.76 | AR (0.41) | ARALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2194045-A1 | SUBSTITUTED PYRAZOLE DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2010-06-09 | — | — | EP | disclosed |