Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3070056 | 0.83 | ALDH1A1 (0.45) | KDM4EALDH1A1PKM | |
| SCHEMBL13308971 | 0.79 | CYP1A2 (0.43) | MAPTALDH1A1PKMLMNASMN1; SMN2 | |
| SCHEMBL13309112 | 0.78 | MBOAT4 (0.39) | CACNA1H | |
| SCHEMBL3069287 | 0.78 | KDM4E (0.45) | KDM4ETP53MAPTPTGDR2ALDH1A1 | |
| SCHEMBL3069345 | 0.78 | AR (0.39) | KDM4ETP53MAPTPTGDR2ALDH1A1 | |
| SCHEMBL13308529 | 0.77 | AR (0.41) | KDM4EMAPTALDH1A1S1PR1PKM | |
| SCHEMBL13308414 | 0.77 | KDM4E (0.40) | KDM4EF11TP53MAPTALDH1A1 | |
| SCHEMBL13308619 | 0.77 | POLB (0.45) | KDM4EPTGDR2LMNAFNTAFNTB | |
| SCHEMBL13308563 | 0.76 | EGLN2 (0.39) | KDM4ETP53MAPTALDH1A1LMNA | |
| SCHEMBL13308598 | 0.76 | HSD17B10 (0.45) | KDM4ETP53MAPTALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2194045-A1 | SUBSTITUTED PYRAZOLE DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2010-06-09 | — | — | EP | disclosed |