Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 6/20 | 0.67 |
| ▸ | CACNB1 | Q02641 | 6/20 | 0.67 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.64 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.64 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.63 |
| ▸ | GPX4 | P36969 | 2/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | BCL2 | P10415 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5688541 | 0.86 | CACNA2D1 (0.60) | CACNA2D1CACNB1CACNA1BCYP2D6CYP3A4 | |
| SCHEMBL12203725 | 0.85 | MGLL (0.84) | CACNA2D1CACNB1CACNA1BCYP2D6CYP3A4 | |
| SCHEMBL16769444 | 0.85 | KMT2A (0.82) | CACNA2D1CACNB1CACNA1BCYP2D6CYP3A4 | |
| SCHEMBL13309468 | 0.85 | KMT2A (0.82) | CACNA2D1CACNB1CACNA1BCYP2D6CYP3A4 | |
| SCHEMBL4649907 | 0.83 | MGLL (0.62) | CACNA2D1CACNB1CACNA1BCYP2D6CACNA1G | |
| SCHEMBL7662352 | 0.83 | CACNA2D1 (0.64) | CACNA2D1CACNB1CACNA1BCACNA1GCACNA1C | |
| SCHEMBL3596897 | 0.81 | CACNA2D1 (0.61) | CACNA2D1CACNB1CACNA1BCACNA1GCACNA1C | |
| SCHEMBL588070 | 0.81 | CACNA2D1 (0.61) | CACNA2D1CACNB1CACNA1BCACNA1GCACNA1C | |
| SCHEMBL7668121 | 0.81 | CHRM2 (0.83) | CACNA2D1CACNB1CACNA1BCYP2D6CYP3A4 | |
| SCHEMBL3395395 | 0.80 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1BCACNA1GCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100145049-A1 | PROCESS FOR MAKING N-(DIPHENYLMETHYL)PIPERAZINES | SYNTHON BV (NL) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145049-A1 | PROCESS FOR MAKING N-(DIPHENYLMETHYL)PIPERAZINES | IL5, PRMT5, IL15 | CACNA2D1 1828/4885CACNB1 2012/4885CACNA1B 574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.