Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.62 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.62 |
| ▸ | CACNA2D1 | P54289 | 6/20 | 0.60 |
| ▸ | CACNB1 | Q02641 | 6/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.60 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.60 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.60 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.59 |
| ▸ | TACR3 | P29371 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13309487 | 0.83 | CACNA2D1 (0.67) | MGLLABHD6CACNA2D1CACNB1CACNA1B | |
| SCHEMBL12203725 | 0.82 | MGLL (0.84) | MGLLABHD6CACNA2D1CACNB1CACNA1B | |
| SCHEMBL4187004 | 0.81 | MGLL (0.68) | MGLLCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL7662352 | 0.80 | CACNA2D1 (0.64) | MGLLABHD6CACNA2D1CACNB1CACNA1B | |
| SCHEMBL5688541 | 0.80 | CACNA2D1 (0.60) | MGLLABHD6CACNA2D1CACNB1CACNA1B | |
| SCHEMBL13309468 | 0.79 | KMT2A (0.82) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL16769444 | 0.79 | KMT2A (0.82) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL3596897 | 0.78 | CACNA2D1 (0.61) | MGLLABHD6CACNA2D1CACNB1CACNA1B | |
| SCHEMBL588070 | 0.78 | CACNA2D1 (0.61) | MGLLABHD6CACNA2D1CACNB1CACNA1B | |
| SCHEMBL7668121 | 0.78 | CHRM2 (0.83) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963296-A2 | OPTICALLY ACTIVE CARBAMATES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS PHARMACEUTICAL INTERMEDIATES | Egis Gyógyszergyár Nyilvánosan Múködö Részvénytársaság (HU) | 2008-09-03 | — | — | EP | claimed |
| WO-2007066163-A2 | OPTICALLY ACTIVE CARBAMATES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS PHARMACEUTICAL INTERMEDIATES | Egis Gyógyszergyár Nyilvanosan Mukodo Reszvenytarsasag (HU) | 2007-06-14 | — | — | WO | claimed |
| EP-1963296-A2 | OPTICALLY ACTIVE CARBAMATES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS PHARMACEUTICAL INTERMEDIATES | Egis Gyógyszergyár Nyilvánosan Múködö Részvénytársaság (HU) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007066163-A2 | OPTICALLY ACTIVE CARBAMATES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS PHARMACEUTICAL INTERMEDIATES | Egis Gyógyszergyár Nyilvanosan Mukodo Reszvenytarsasag (HU) | 2007-06-14 | — | — | WO | disclosed |