Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 9/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13309851 | 1.00 | DNM2 (0.49) | DNM2TLR8ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13309820 | 1.00 | DNM2 (0.49) | DNM2TLR8ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13309838 | 1.00 | DNM2 (0.49) | DNM2TLR8ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13309871 | 1.00 | DNM2 (0.49) | DNM2TLR8ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13309898 | 0.80 | PFKFB3 (0.46) | DNM2TLR8ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13309831 | 0.76 | LATS1 (0.52) | DNM2TLR8ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13309843 | 0.76 | LATS1 (0.52) | DNM2TLR8ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13309859 | 0.76 | LATS1 (0.52) | DNM2TLR8ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13309815 | 0.76 | LATS1 (0.52) | DNM2TLR8ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13309794 | 0.76 | DNM2 (0.48) | DNM2TLR8ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7731985-B2 | 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-06-08 | — | — | US | disclosed |
| US-7731985-B2 | 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-06-08 | — | — | US | disclosed |