Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ATP4A | P20648 | 2/20 | 0.32 |
| ▸ | ATP4B | P51164 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13309871 | 0.80 | DNM2 (0.49) | TLR8ALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL13309803 | 0.80 | DNM2 (0.49) | TLR8ALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL13309838 | 0.80 | DNM2 (0.49) | TLR8ALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL13309851 | 0.80 | DNM2 (0.49) | TLR8ALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL13309893 | 0.79 | PFKFB3 (0.45) | PFKFB3TLR8ALDH1A1TSHRCYP3A4 | |
| SCHEMBL13309889 | 0.79 | PFKFB3 (0.46) | PFKFB3TLR8ALDH1A1TSHRCYP3A4 | |
| SCHEMBL13309895 | 0.78 | PFKFB3 (0.48) | PFKFB3TLR8ALDH1A1TSHRCYP3A4 | |
| SCHEMBL13309890 | 0.78 | ABCG2 (0.49) | PFKFB3ALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL13309894 | 0.78 | PFKFB3 (0.55) | PFKFB3TLR8ALDH1A1TSHRCYP3A4 | |
| SCHEMBL11779958 | 0.75 | ESR1 (0.46) | PFKFB3TLR8ALDH1A1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7731985-B2 | 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-06-08 | — | — | US | disclosed |
| US-7731985-B2 | 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-06-08 | — | — | US | disclosed |