Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 11/20 | 0.56 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13309802 | 1.00 | DNM2 (0.56) | DNM2TLR8ALDH1A1TP53TSHR | |
| SCHEMBL3428347 | 1.00 | DNM2 (0.56) | DNM2TLR8ALDH1A1TP53TSHR | |
| SCHEMBL13309868 | 1.00 | DNM2 (0.56) | DNM2TLR8ALDH1A1TP53TSHR | |
| SCHEMBL13309819 | 1.00 | DNM2 (0.56) | DNM2TLR8ALDH1A1TP53TSHR | |
| SCHEMBL13309832 | 0.81 | TLR8 (0.61) | DNM2TLR8ALDH1A1TP53TSHR | |
| SCHEMBL13309844 | 0.81 | TLR8 (0.61) | DNM2TLR8ALDH1A1TP53TSHR | |
| SCHEMBL13309816 | 0.81 | TLR8 (0.61) | DNM2TLR8ALDH1A1TP53TSHR | |
| SCHEMBL13309799 | 0.81 | TLR8 (0.61) | DNM2TLR8ALDH1A1TP53TSHR | |
| SCHEMBL13309860 | 0.81 | TLR8 (0.61) | DNM2TLR8ALDH1A1TP53TSHR | |
| SCHEMBL13329946 | 0.80 | DNM2 (0.81) | DNM2TLR8ALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7731985-B2 | 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-06-08 | — | — | US | disclosed |
| US-7731985-B2 | 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-06-08 | — | — | US | disclosed |