Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 12/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13329945 | 1.00 | DNM2 (0.81) | DNM2ALDH1A1MAPK1LMNATP53 | |
| SCHEMBL1194281 | 0.98 | DNM2 (0.78) | DNM2ALDH1A1MAPK1LMNATP53 | |
| SCHEMBL13329951 | 0.97 | DNM2 (0.77) | DNM2ALDH1A1MAPK1LMNATP53 | |
| SCHEMBL16608857 | 0.93 | ALDH1A1 (0.73) | DNM2ALDH1A1MAPK1LMNATP53 | |
| SCHEMBL25474229 | 0.90 | DNM2 (1.00) | DNM2ALDH1A1MAPK1LMNATP53 | |
| SCHEMBL16608745 | 0.86 | DNM2 (0.61) | DNM2ALDH1A1MAPK1LMNATP53 | |
| SCHEMBL13329947 | 0.85 | LMNA (0.83) | DNM2ALDH1A1MAPK1LMNATP53 | |
| SCHEMBL13309816 | 0.85 | TLR8 (0.61) | DNM2ALDH1A1MAPK1LMNATP53 | |
| SCHEMBL13309799 | 0.85 | TLR8 (0.61) | DNM2ALDH1A1MAPK1LMNATP53 | |
| SCHEMBL13309860 | 0.85 | TLR8 (0.61) | DNM2ALDH1A1MAPK1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7722893-B2 | Use of substitute 2,4-bis (alkylamino) pyrimidines or quinzolines as antimicrobials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-7722893-B2 | Use of substitute 2,4-bis (alkylamino) pyrimidines or quinzolines as antimicrobials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |