Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PRP4K | Q13523 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2061998 | 0.88 | KCNA5 (0.54) | HPGDALDH1A1KDM4ERCE1KCNA5 | |
| SCHEMBL8568942 | 0.81 | HPGD (0.57) | HPGDALDH1A1KDM4ERCE1KCNA5 | |
| SCHEMBL27482218 | 0.81 | KCNA5 (0.48) | HPGDALDH1A1KDM4ERCE1KCNA5 | |
| SCHEMBL19318518 | 0.76 | HPGD (0.53) | HPGDALDH1A1KDM4ERCE1HDAC1 | |
| SCHEMBL8018113 | 0.76 | KCNA5 (0.56) | KCNA5HDAC1HDAC10HDAC6KDM4A | |
| SCHEMBL30159605 | 0.76 | KCNA5 (0.56) | KCNA5HDAC1HDAC10HDAC6KDM4A | |
| SCHEMBL6676878 | 0.75 | KCNA5 (0.46) | HPGDALDH1A1KDM4ERCE1KCNA5 | |
| SCHEMBL27273924 | 0.75 | NQO2 (0.46) | HPGDALDH1A1KDM4ERCE1KCNA5 | |
| SCHEMBL10416108 | 0.74 | HPGD (0.57) | HPGDALDH1A1KDM4ERCE1HDAC1 | |
| SCHEMBL28584573 | 0.73 | ALDH1A1 (0.47) | HPGDALDH1A1KDM4ERCE1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2202231-A1 | 2,3-DIHYDROIMINOISOINDOLE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2010-06-30 | — | — | EP | disclosed |