SCHEMBL13310900

SCHEMBL13310900

COCC(C)Nc1nc(N2CCCC2)nc(NCCCOC(=O)COCC(=O)O)c1N=Nc1nn(-c2nc3ccccc3s2)cc1C#N

nearest known ligand 0.31

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.31
▸ KDM4E B2RXH2 2/20 0.31
▸ ALDH1A1 P00352 2/20 0.31
▸ POLB P06746 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ HTT P42858 1/20 0.31
▸ RECQL P46063 1/20 0.31
▸ MAPK1 P28482 1/20 0.30
▸ CASP1 P29466 1/20 0.30
▸ RAB9A P51151 1/20 0.30
▸ HSD17B10 Q99714 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ GMNN O75496 1/20 0.30
▸ LMNA P02545 1/20 0.30
▸ PMP22 Q01453 1/20 0.30
▸ KMT2A Q03164 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13347765 0.95 MAPT (0.32) MAPTKDM4EALDH1A1POLBHPGD
SCHEMBL13347799 0.82 BRD4 (0.30) —
SCHEMBL13472082 0.82 — —
SCHEMBL10233109 0.81 MAPT (0.35) MAPTKDM4EALDH1A1POLBRAB9A
SCHEMBL13347798 0.81 BRD4 (0.30) —
SCHEMBL13610063 0.80 MAPT (0.33) MAPTKDM4EALDH1A1RAB9ASMN1; SMN2
SCHEMBL13610085 0.78 — —
SCHEMBL14506740 0.78 MAPT (0.32) MAPTKDM4EALDH1A1POLBRAB9A
SCHEMBL10233105 0.78 MAPT (0.33) MAPTRAB9A
SCHEMBL10233110 0.77 MAPT (0.32) MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293436-B2 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2012-10-23 — — US disclosed
US-8293436-B2 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2012-10-23 — — US disclosed
US-7740995-B2 Azo compound, colored curable composition, color filter and manufacturing method therefor FUJIFILM CORPORATION (JP) 2010-06-22 — — US disclosed
US-20100104976-A1 OXIME DERIVATIVE, PHOTOPOLYMERIZABLE COMPOSITION, COLOR FILTER, AND PROCESS FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2010-04-29 — — US disclosed
US-20100104976-A1 OXIME DERIVATIVE, PHOTOPOLYMERIZABLE COMPOSITION, COLOR FILTER, AND PROCESS FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2010-04-29 — — US disclosed
US-7674503-B2 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2010-03-09 — — US disclosed
US-7674503-B2 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2010-03-09 — — US disclosed
US-20070203255-A1 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2007-08-30 — — US disclosed
US-20070203255-A1 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2007-08-30 — — US disclosed
US-20070037076-A1 Pyrimidine azo dye, curable tri- or higher-functional (meth)acrylic ester monomers, alkali-soluble (meth)acrylic resin binder, photoinitiators ( traizines, benzophenones, lophine dimer etc.); curing, developing; for forming a color filter for use in a liquid crystal display FUJI PHOTO FILM CO., LTD. 2007-02-15 — — US disclosed
US-20070037076-A1 Pyrimidine azo dye, curable tri- or higher-functional (meth)acrylic ester monomers, alkali-soluble (meth)acrylic resin binder, photoinitiators ( traizines, benzophenones, lophine dimer etc.); curing, developing; for forming a color filter for use in a liquid crystal display FUJI PHOTO FILM CO., LTD. 2007-02-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100104976-A1 OXIME DERIVATIVE, PHOTOPOLYMERIZABLE COMPOSITION, COLOR FILTER, AND PROCESS FOR PRODUCING THE SAME PPOX, CYBA, HBB MAPT 2701/4885KDM4E 228/4885ALDH1A1 617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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