Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.35 |
| ▸ | PNP | P00491 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanine SCHEMBL16389311 | 0.76 | PNP (0.44) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| Isoxanthopterin SCHEMBL9148336 | 0.70 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| Xanthopterin SCHEMBL906221 | 0.70 | ALDH1A1 (0.54) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| Xanthopterin SCHEMBL2489021 | 0.69 | ALDH1A1 (0.53) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| SCHEMBL7677673 | 0.68 | ALDH1A1 (0.47) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| SCHEMBL7682920 | 0.68 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| SCHEMBL31149845 | 0.67 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| SCHEMBL4297911 | 0.67 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| SCHEMBL4273098 | 0.67 | NSD2 (0.51) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| SCHEMBL7683620 | 0.66 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12473287-B2 | Synthetic co-crystals of anhydrous guanine and process for preparing the same | ECOCRYSTAL LTD. (IL) | 2025-11-18 | — | — | US | claimed |
| US-20240208977-A1 | SYNTHETIC CO-CRYSTALS OF ANHYDROUS GUANINE AND PROCESS FOR PREPARING THE SAME | ECOCRYSTAL LTD. (IL) | 2024-06-27 | — | — | US | claimed |
| US-11858936-B2 | Synthetic co-crystals of anhydrous guanine and process for preparing the same | GUR, Dvir (IL) | 2024-01-02 | — | — | US | claimed |
| US-20220098199-A1 | SYNTHETIC CO-CRYSTALS OF ANHYDROUS GUANINE AND PROCESS FOR PREPARING THE SAME | GUR, Dvir (IL) | 2022-03-31 | — | — | US | claimed |
| WO-2019175332-A1 | BH4 PATHWAY INHIBITION AND USE THEREOF FOR TREATING T-CELL MEDIATED AUTOIMMUNE DISEASES OR HYPERSENSITIVITY | IMBA - INSTITUT FÜR MOLEKULARE BIOTECHNOLOGIE GMBH (AT) | 2019-09-19 | — | — | WO | claimed |
| US-20190211016-A1 | SYNTHETIC CO-CRYSTALS OF ANHYDROUS GUANINE AND PROCESS FOR PREPARING THE SAME | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2019-07-11 | — | — | US | claimed |
| CN-109946412-A | A kind of body fluid pterin spectrum detection kit and its use | 上海产业技术研究院 | 2019-06-28 | — | — | CN | claimed |
| CN-103529005-B | High-efficiency capillary electrophoresis-laser induced fluorescence detection equipment and application of diagnostic kit in early diagnosis of breast cancer | 江苏禾尔思生物科技有限公司 | 2017-02-15 | — | — | CN | claimed |
| CN-103529196-A | Kit used for detecting early-stage breast cancer | JIANGSU HEERSI BIOTECHNOLOGY CO LTD | 2014-01-22 | — | — | CN | claimed |
| CN-103529005-A | Application of high-efficiency capillary electrophoresis-laser induced fluorescence detection device and diagnostic kit in early diagnosis of mammary cancer | JIANGSU HEERSI BIOTECHNOLOGY CO LTD | 2014-01-22 | — | — | CN | claimed |
| US-6576105-B1 | Cancer monitoring and screening | TRUMAN STATE UNIVERSITY | 2003-06-10 | — | — | US | claimed |
| US-6358953-B1 | ADMINISTERING PTERIN METAL COMPLEX AS ANTICARCINOGENIC AGENTS AND VIRICIDES | Moheno, Phillip B. B. | 2002-03-19 | — | — | US | claimed |
| EP-1123294-A1 | NOVEL PTERIN ANTINEOPLASTIC AGENTS | Moheno, Phillip B. B. (US) | 2001-08-16 | — | — | EP | claimed |
| WO-2000023448-A1 | NOVEL PTERIN ANTINEOPLASTIC AGENTS | MOHENO PHILLIP B B (US) | 2000-04-27 | — | — | WO | claimed |
| US-5534514-A | ANTITUMOR AGENTS OR FOR TREATMENT OF LEUKEMIA USING MIXTURES OF XANTHOPTERIN AND ISOXANTHOPTERIN SUSPENSION OF CARRIER | SAN DIEGO STATE UNIVERSITY (US) | 1996-07-09 | — | — | US | claimed |
| EP-0248084-B1 | MODULATION OF ANIMAL CELLULAR RESPONSES WITH COMPOSITIONS CONTAINING ISOXANTHOPTERIN-8-(1'-BETA-ALDOGLYCOSIDYL) DERIVATIVES | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1992-11-25 | — | — | EP | claimed |
| US-4900675-A | ENHANCING IMMUNE RESPONSE | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1990-02-13 | — | — | US | claimed |
| EP-0248084-A4 | MODULATION OF ANIMAL CELLULAR RESPONSES WITH COMPOSITIONS CONTAINING ISOXANTHOPTERIN-8-(1'-BETA-ALDOGLYCOSIDYL) DERIVATIVES. | SCRIPPS CLINIC RES (US) | 1988-03-30 | — | — | EP | claimed |
| EP-0248084-A1 | MODULATION OF ANIMAL CELLULAR RESPONSES WITH COMPOSITIONS CONTAINING ISOXANTHOPTERIN-8-(1'-BETA-ALDOGLYCOSIDYL) DERIVATIVES. | SCRIPPS CLINIC RES (US) | 1987-12-09 | — | — | EP | claimed |
| WO-1987003617-A1 | MODULATION OF ANIMAL CELLULAR RESPONSES WITH COMPOSITIONS CONTAINING ISOXANTHOPTERIN-8-(1'-BETA-ALDOGLYCOSIDYL) DERIVATIVES | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1987-06-18 | — | — | WO | claimed |