Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PNP | P00491 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398502 | 0.87 | KDM4E (0.38) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| SCHEMBL7682920 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| SCHEMBL4297911 | 0.75 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| SCHEMBL7683616 | 0.74 | AKR1B1 (0.57) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| SCHEMBL4816470 | 0.73 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| SCHEMBL7677673 | 0.73 | ALDH1A1 (0.47) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| SCHEMBL7677720 | 0.73 | AKR1B1 (0.60) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| Pterine SCHEMBL64321 | 0.72 | ALDH1A1 (0.41) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| SCHEMBL29357615 | 0.71 | NOS1 (0.55) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| SCHEMBL398501 | 0.71 | NOS1 (0.55) | KDM4EALDH1A1HSD17B10LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358953-B1 | ADMINISTERING PTERIN METAL COMPLEX AS ANTICARCINOGENIC AGENTS AND VIRICIDES | Moheno, Phillip B. B. | 2002-03-19 | — | — | US | disclosed |
| EP-1123294-A1 | NOVEL PTERIN ANTINEOPLASTIC AGENTS | Moheno, Phillip B. B. (US) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000023448-A1 | NOVEL PTERIN ANTINEOPLASTIC AGENTS | MOHENO PHILLIP B B (US) | 2000-04-27 | — | — | WO | disclosed |