Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29386513 | 0.88 | TLR2 (0.39) | SMYD2CYP3A4HTTSMN1; SMN2TLR2 | |
| SCHEMBL22557768 | 0.86 | SMN1; SMN2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2KDM4E | |
| SCHEMBL13311307 | 0.86 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2KMT2A | |
| SCHEMBL8071091 | 0.85 | SMN1; SMN2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2KMT2A | |
| SCHEMBL8070836 | 0.85 | SMN1; SMN2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2KMT2A | |
| SCHEMBL12192745 | 0.82 | SMYD2 (0.36) | SMYD2CYP3A4HTTSMN1; SMN2KDM4E | |
| SCHEMBL13311353 | 0.82 | SMYD2 (0.33) | SMYD2CYP3A4HTTSMN1; SMN2KDM4E | |
| SCHEMBL14315531 | 0.81 | SMYD2 (0.35) | SMYD2CYP3A4HTTSMN1; SMN2KDM4E | |
| SCHEMBL28950788 | 0.81 | L3MBTL1 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2TLR2 | |
| SCHEMBL14296503 | 0.80 | CYP3A4 (0.34) | SMYD2CYP3A4HTTSMN1; SMN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024071371-A1 | HETEROCYCLIC COMPOUND | ユビエンス株式会社 | 2024-04-04 | — | — | WO | disclosed |
| US-20100137188-A1 | FORMULATIONS COMPRISING CYCLIC COMPOUNDS | CAPSUGEL BELGIUM (BE) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137188-A1 | FORMULATIONS COMPRISING CYCLIC COMPOUNDS | SLC2A1, SLC2A4, SLC2A9 | SMYD2 379/4885CYP3A4 3013/4885HTT 3169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.