Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 10/20 | 0.84 |
| ▸ | USP2 | O75604 | 5/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | ACP1 | P24666 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.62 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HBB | P68871 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14095300 | 0.91 | TLR9 (1.00) | TLR9USP2ALOX15HSD17B10ACP1 | |
| SCHEMBL14259846 | 0.90 | TLR9 (0.68) | TLR9USP2ALOX15HSD17B10ACP1 | |
| SCHEMBL1085597 | 0.84 | ACP1 (0.87) | TLR9USP2ALOX15HSD17B10ACP1 | |
| SCHEMBL12175518 | 0.83 | TLR9 (1.00) | TLR9USP2ALOX15HSD17B10TSHR | |
| SCHEMBL29360163 | 0.83 | TLR9 (1.00) | TLR9USP2ALOX15HSD17B10TSHR | |
| SCHEMBL1085510 | 0.83 | ACP1 (0.70) | TLR9USP2ALOX15HSD17B10ACP1 | |
| SCHEMBL13312485 | 0.83 | ACP1 (0.70) | TLR9USP2ALOX15HSD17B10ACP1 | |
| SCHEMBL13312422 | 0.80 | TLR9 (0.58) | TLR9ACP1KMT2ALMNA | |
| SCHEMBL14233114 | 0.79 | TLR9 (0.68) | TLR9USP2ALOX15HSD17B10ACP1 | |
| SCHEMBL1085859 | 0.78 | ACP1 (0.71) | TLR9USP2ALOX15HSD17B10ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160314-A1 | Small Molecule Inhibitors of Toll-Like Receptor 9 | LIPFORD GRAYSON B | 2010-06-24 | — | — | US | disclosed |
| US-20100160314-A1 | Small Molecule Inhibitors of Toll-Like Receptor 9 | LIPFORD GRAYSON B | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160314-A1 | Small Molecule Inhibitors of Toll-Like Receptor 9 | TLR9, TLR3, TLR1 | TLR9 1/4885USP2 4571/4885ALOX15 1984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.