Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 7/20 | 0.68 |
| ▸ | ACP1 | P24666 | 3/20 | 0.63 |
| ▸ | AURKA | O14965 | 3/20 | 0.59 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | GBA1 | P04062 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13312480 | 0.90 | TLR9 (0.84) | TLR9ACP1USP2HSD17B10ALOX15 | |
| SCHEMBL1085411 | 0.83 | ACP1 (0.87) | TLR9ACP1USP2HSD17B10ALOX15 | |
| SCHEMBL14259847 | 0.83 | ACP1 (0.69) | TLR9ACP1USP2HSD17B10ALOX15 | |
| SCHEMBL1085090 | 0.82 | ACP1 (0.84) | TLR9ACP1USP2HSD17B10ALOX15 | |
| SCHEMBL14095300 | 0.81 | TLR9 (1.00) | TLR9ACP1USP2HSD17B10ALOX15 | |
| SCHEMBL14259833 | 0.77 | ACP1 (0.70) | ACP1 | |
| SCHEMBL31453017 | 0.77 | TLR9 (0.72) | TLR9ACP1USP2HSD17B10ALOX15 | |
| SCHEMBL3460750 | 0.76 | ACP1 (0.74) | TLR9ACP1USP2HSD17B10ALOX15 | |
| SCHEMBL1084058 | 0.76 | CYP1A2 (0.65) | TLR9ACP1USP2HSD17B10ALOX15 | |
| SCHEMBL14095324 | 0.75 | TLR9 (1.00) | TLR9ACP1USP2HSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008030455-A2 | SMALL MOLECULE INHIBITORS OF TOLL-LIKE RECEPTOR 9 | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2008-03-13 | — | — | WO | disclosed |