Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GNPAT | O15228 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 5/20 | 0.39 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.39 |
| ▸ | PSMD11 | O00231 | 2/20 | 0.39 |
| ▸ | PSMD12 | O00232 | 2/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.39 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.39 |
| ▸ | PSMD3 | O43242 | 2/20 | 0.39 |
| ▸ | PSMC3 | P17980 | 2/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.39 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.39 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.39 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.39 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.39 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13625026 | 1.00 | SYK (0.42) | SYKALDH1A1MEN1KMT2AGNPAT | |
| SCHEMBL13313868 | 1.00 | SYK (0.42) | SYKALDH1A1MEN1KMT2AGNPAT | |
| SCHEMBL13313886 | 1.00 | SYK (0.42) | SYKALDH1A1MEN1KMT2AGNPAT | |
| SCHEMBL14014083 | 0.89 | ALDH1A1 (0.42) | SYKALDH1A1MEN1KMT2AGNPAT | |
| SCHEMBL13157948 | 0.88 | GNPAT (0.41) | SYKMEN1KMT2AGNPATCA12 | |
| SCHEMBL13313862 | 0.88 | SYK (0.49) | SYKCAPN1MMP8 | |
| SCHEMBL13038592 | 0.88 | SYK (0.49) | SYKCAPN1MMP8 | |
| SCHEMBL13010184 | 0.86 | MEN1 (0.42) | SYKMEN1KMT2AGNPATCA12 | |
| SCHEMBL13625031 | 0.85 | CTSB (0.42) | SYKALDH1A1MEN1KMT2AGNPAT | |
| SCHEMBL13625027 | 0.85 | CTSB (0.42) | SYKALDH1A1MEN1KMT2AGNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100136063-A1 | Immunotherapy for Treatment of Amyloid-Related Disorders Using Encapsulated Beta-Amyloid Peptides | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-06-03 | — | — | US | disclosed |
| US-7618944-B2 | Encapsulating in micelle which is a block copolymer containing hydrophilic and hydrophobic blocks | INTEZYNE TECHNOLOGIES, INC. (US) | 2009-11-17 | — | — | US | disclosed |
| US-20080274965-A1 | ENCAPSULATED AMYLOID-BETA PEPTIDES | INTEZYNE TECHNOLOGIES, INC. (US) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100136063-A1 | Immunotherapy for Treatment of Amyloid-Related Disorders Using Encapsulated Beta-Amyloid Peptides | IAPP, APP, TTR | SYK 1417/4885ALDH1A1 4414/4885MEN1 271/4885 |
| US-20080274965-A1 | ENCAPSULATED AMYLOID-BETA PEPTIDES | IAPP, APP, TTR | SYK 2774/4885ALDH1A1 4688/4885MEN1 227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.