Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | STK25 | O00506 | 1/20 | 0.39 |
| ▸ | YEATS4 | O95619 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13315133 | 0.83 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3548879 | 0.82 | MAPK14 (0.43) | HPGDPTGS2MAPK14 | |
| SCHEMBL13315141 | 0.77 | MAPT (0.43) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL13487583 | 0.75 | MAPK14 (0.49) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3545622 | 0.72 | CNR2 (0.34) | SMN1; SMN2CNR2MAPK14 | |
| SCHEMBL3220088 | 0.71 | MAPK14 (0.55) | ALDH1A1KDM4EHPGDTSHRNPSR1 | |
| SCHEMBL3244391 | 0.71 | MAPK14 (0.53) | MAPK14 | |
| SCHEMBL13315136 | 0.67 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL13315099 | 0.67 | YEATS4 (0.50) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL13315098 | 0.64 | YEATS4 (0.50) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741479-B2 | Urea inhibitors of MAP kinases | LOCUS PHARMACEUTICALS, INC. (US) | 2010-06-22 | — | — | US | disclosed |
| US-20100041642-A1 | UREA INHIBITORS OF MAP KINASES | LOCUS PHARMACEUTICALS, INC. (US) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041642-A1 | UREA INHIBITORS OF MAP KINASES | MAP4K2, MAP3K1, MAP3K20 | MEN1 3623/4885KMT2A 3153/4885ALDH1A1 3577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.