Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 13/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.45 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | HBB | P68871 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13315803 | 0.83 | SLC16A3 (0.53) | SLC16A3USP2CASP1BRCA1CASP7 | |
| SCHEMBL13315806 | 0.81 | USP2 (0.47) | SLC16A3USP2CASP1BRCA1CASP7 | |
| SCHEMBL13315794 | 0.77 | HDAC3 (0.51) | HDAC3HDAC1HDAC6HDAC2HDAC10 | |
| SCHEMBL13348929 | 0.76 | SLC16A3 (0.49) | SLC16A3USP2CASP1BRCA1CASP7 | |
| SCHEMBL13315804 | 0.74 | SLC16A3 (0.44) | SLC16A3USP2CASP1BRCA1CASP7 | |
| SCHEMBL13315802 | 0.73 | KDM4E (0.50) | HDAC3HDAC1HDAC6HDAC2HDAC10 | |
| SCHEMBL13315813 | 0.72 | HDAC3 (0.46) | HDAC3HDAC1HDAC6HDAC2HDAC10 | |
| SCHEMBL23872036 | 0.68 | SLC16A3 (0.67) | SLC16A3USP2CASP1BRCA1CASP7 | |
| SCHEMBL9351972 | 0.67 | SLC16A3 (0.68) | SLC16A3USP2CASP1BRCA1CASP7 | |
| SCHEMBL12216211 | 0.66 | USP2 (0.65) | SLC16A3USP2CASP1BRCA1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745229-B2 | Chemoselective fluorgenic molecular linkers and methods for their preparation and use | UNIVERSITY OF SOUTH CAROLINA | 2010-06-29 | — | — | US | disclosed |
| US-7745229-B2 | Chemoselective fluorgenic molecular linkers and methods for their preparation and use | UNIVERSITY OF SOUTH CAROLINA | 2010-06-29 | — | — | US | disclosed |
| US-20070224695-A1 | Chemoselective Fluorgenic Molecular Linkers and Methods for Their Preparation and Use | UNIVERSITY OF SOUTH CAROLINA (US) | 2007-09-27 | — | — | US | disclosed |
| US-20070224695-A1 | Chemoselective Fluorgenic Molecular Linkers and Methods for Their Preparation and Use | UNIVERSITY OF SOUTH CAROLINA (US) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070224695-A1 | Chemoselective Fluorgenic Molecular Linkers and Methods for Their Preparation and Use | KIT, HLCS, ALK | HDAC3 1426/4885HDAC1 2120/4885HDAC6 1095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.