Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | USP2 | O75604 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13315794 | 0.88 | HDAC3 (0.51) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL13315813 | 0.82 | HDAC3 (0.46) | KDM4EALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL3550061 | 0.82 | MAPT (0.60) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL13315799 | 0.80 | MAPT (0.58) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL13348930 | 0.75 | ADRA1D (0.50) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL13315798 | 0.73 | CA12 (0.45) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL13315809 | 0.73 | HDAC3 (0.45) | KDM4EALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL13315800 | 0.73 | MAPT (0.52) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL12527306 | 0.71 | MAPT (0.45) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL13315801 | 0.71 | CYP19A1 (0.51) | KDM4EMAPTALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745229-B2 | Chemoselective fluorgenic molecular linkers and methods for their preparation and use | UNIVERSITY OF SOUTH CAROLINA | 2010-06-29 | — | — | US | disclosed |
| US-7745229-B2 | Chemoselective fluorgenic molecular linkers and methods for their preparation and use | UNIVERSITY OF SOUTH CAROLINA | 2010-06-29 | — | — | US | disclosed |
| US-20070224695-A1 | Chemoselective Fluorgenic Molecular Linkers and Methods for Their Preparation and Use | UNIVERSITY OF SOUTH CAROLINA (US) | 2007-09-27 | — | — | US | disclosed |
| US-20070224695-A1 | Chemoselective Fluorgenic Molecular Linkers and Methods for Their Preparation and Use | UNIVERSITY OF SOUTH CAROLINA (US) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070224695-A1 | Chemoselective Fluorgenic Molecular Linkers and Methods for Their Preparation and Use | KIT, HLCS, ALK | KDM4E 1692/4885MAPT 4747/4885ALDH1A1 1386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.