Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13316140 | 1.00 | PPARG (1.00) | PPARGNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL13316084 | 0.91 | PPARG (1.00) | PPARG | |
| SCHEMBL13316065 | 0.91 | PPARG (1.00) | PPARG | |
| SCHEMBL13316144 | 0.91 | PPARG (0.89) | PPARG | |
| SCHEMBL13316083 | 0.91 | PPARG (0.82) | PPARGNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL13316139 | 0.89 | PPARG (0.83) | PPARG | |
| SCHEMBL13316095 | 0.89 | PPARG (1.00) | PPARGNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL13316096 | 0.87 | PPARG (1.00) | PPARGNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL13316166 | 0.85 | PPARG (0.93) | PPARGNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL13316081 | 0.85 | PPARG (0.92) | PPARGNPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741323-B2 | Indene derivatives and process for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-22 | — | — | US | disclosed |
| US-20070185109-A1 | Idene derivatives and process for the preparation thereof | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185109-A1 | Idene derivatives and process for the preparation thereof | INSR, PPARD, GPR119 | PPARG 5/4885NPC1 469/4885RAB9A 2389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.