Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 3/20 | 0.30 |
| ▸ | FNTB | P49356 | 3/20 | 0.30 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.30 |
| ▸ | DHPS | P49366 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13316234 | 0.89 | CYP11B2 (0.37) | CYP11B2CYP11B1FNTAFNTB | |
| SCHEMBL3568461 | 0.84 | CYP11B2 (0.61) | CYP11B2CYP11B1FNTAFNTBPGGT1B | |
| SCHEMBL3570686 | 0.82 | CYP11B2 (0.55) | CYP11B2CYP11B1CYP3A4NPSR1 | |
| SCHEMBL8360550 | 0.82 | CYP11B2 (0.55) | CYP11B2CYP11B1MEN1KMT2ACYP3A4 | |
| SCHEMBL3466041 | 0.75 | CYP11B2 (0.65) | CYP11B2CYP11B1FNTAFNTBPGGT1B | |
| SCHEMBL3466043 | 0.75 | CYP11B2 (0.65) | CYP11B2CYP11B1FNTAFNTBPGGT1B | |
| SCHEMBL3568308 | 0.73 | CYP11B2 (0.49) | CYP11B2CYP11B1FNTAFNTBPGGT1B | |
| SCHEMBL3566481 | 0.69 | CYP11B2 (0.57) | CYP11B2CYP11B1FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL3571119 | 0.68 | CYP11B2 (0.56) | CYP11B2CYP11B1FNTAFNTBPGGT1B | |
| SCHEMBL3465432 | 0.67 | CYP11B2 (0.55) | CYP11B2CYP11B1FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732603-B2 | Organic compounds as agents for the treatment of aldosterone mediated conditions | NOVARTIS AG (CH) | 2010-06-08 | — | — | US | disclosed |