Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 5/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CLPP | Q16740 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3570686 | 0.90 | CYP11B2 (0.55) | CYP11B2NPSR1CYP11B1SCN9ACHRM2 | |
| SCHEMBL3568461 | 0.82 | CYP11B2 (0.61) | CYP11B2NPSR1CYP11B1FNTAFNTB | |
| SCHEMBL13316233 | 0.82 | CYP11B2 (0.46) | CYP11B2NPSR1CYP11B1CYP3A4FNTA | |
| SCHEMBL3465432 | 0.75 | CYP11B2 (0.55) | CYP11B2CYP11B1FNTAFNTB | |
| SCHEMBL3465435 | 0.75 | CYP11B2 (0.55) | CYP11B2CYP11B1FNTAFNTB | |
| SCHEMBL3984392 | 0.74 | CYP11B2 (0.58) | CYP11B2NPSR1CYP11B1ALDH1A1POLB | |
| SCHEMBL3466043 | 0.74 | CYP11B2 (0.65) | CYP11B2CYP11B1FNTAFNTB | |
| SCHEMBL3466041 | 0.74 | CYP11B2 (0.65) | CYP11B2CYP11B1FNTAFNTB | |
| SCHEMBL3464840 | 0.74 | CYP11B2 (0.62) | CYP11B2CYP11B1FNTAFNTB | |
| SCHEMBL3464837 | 0.74 | CYP11B2 (0.62) | CYP11B2CYP11B1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014914-A1 | ORGANIC COMPOUNDS AS AGENTS FOR THE TREATMENT OF ALDOSTERONE MEDIATED CONDITIONS | NOVARTIS AG (CH) | 2004-02-19 | — | — | WO | disclosed |