Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13316677 | 0.85 | METTL3 (0.33) | KMT2AMRGPRX4 | |
| SCHEMBL13316616 | 0.84 | — | — | |
| SCHEMBL13316618 | 0.83 | — | — | |
| SCHEMBL13316652 | 0.76 | — | — | |
| SCHEMBL13349598 | 0.73 | CXCR2 (0.32) | — | |
| SCHEMBL13349597 | 0.72 | CXCR2 (0.34) | — | |
| SCHEMBL12107889 | 0.72 | METTL3 (0.42) | KMT2AALDH1A1HPGDMRGPRX4 | |
| SCHEMBL13316678 | 0.72 | METTL3 (0.35) | — | |
| SCHEMBL13349710 | 0.71 | CXCR2 (0.32) | — | |
| SCHEMBL13316679 | 0.71 | METTL3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745459-B2 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-06-29 | — | — | US | disclosed |