Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 3/20 | 0.31 |
| ▸ | PDE5A | O76074 | 2/20 | 0.30 |
| ▸ | PDE6D | O43924 | 1/20 | 0.30 |
| ▸ | PDE6A | P16499 | 1/20 | 0.30 |
| ▸ | PDE6G | P18545 | 1/20 | 0.30 |
| ▸ | PDE6B | P35913 | 1/20 | 0.30 |
| ▸ | PDE6C | P51160 | 1/20 | 0.30 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13349622 | 0.85 | METTL3 (0.34) | METTL3CSF1RCTSAMRGPRX4KMT2A | |
| SCHEMBL13316617 | 0.85 | KMT2A (0.32) | MRGPRX4KMT2A | |
| SCHEMBL13316678 | 0.85 | METTL3 (0.35) | METTL3CSF1REGFR | |
| SCHEMBL13316679 | 0.84 | METTL3 (0.32) | METTL3CSF1R | |
| SCHEMBL13349641 | 0.76 | METTL3 (0.38) | METTL3CSF1RCTSASMN1; SMN2KMT2A | |
| SCHEMBL13349640 | 0.76 | METTL3 (0.40) | METTL3CSF1RKMT2AMEN1POLB | |
| SCHEMBL13349627 | 0.75 | METTL3 (0.38) | METTL3CSF1RCTSASMN1; SMN2KMT2A | |
| SCHEMBL13349605 | 0.73 | METTL3 (0.36) | METTL3CSF1RCTSAKMT2AMEN1 | |
| SCHEMBL13316616 | 0.73 | — | — | |
| SCHEMBL13349643 | 0.72 | METTL3 (0.35) | METTL3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745459-B2 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-06-29 | — | — | US | disclosed |