Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13331532 | 0.82 | CYP19A1 (0.35) | — | |
| SCHEMBL31369324 | 0.79 | APLNR (0.33) | GBA1 | |
| SCHEMBL30853171 | 0.79 | APLNR (0.33) | GBA1 | |
| SCHEMBL13316649 | 0.78 | APLNR (0.34) | GBA1 | |
| SCHEMBL13332297 | 0.77 | APLNR (0.34) | — | |
| SCHEMBL13349599 | 0.76 | DGAT1 (0.30) | — | |
| SCHEMBL30262447 | 0.74 | APLNR (0.34) | — | |
| SCHEMBL26814295 | 0.74 | APLNR (0.34) | — | |
| SCHEMBL13316652 | 0.73 | — | — | |
| SCHEMBL30931230 | 0.72 | APLNR (0.36) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745459-B2 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-06-29 | — | — | US | disclosed |