Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5052617 | 0.83 | PDE10A (0.43) | GAAHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL1019767 | 0.81 | PIK3CG (0.33) | GAAHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL5056012 | 0.81 | RAB9A (0.44) | GAAHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL13896433 | 0.76 | PDE10A (0.40) | GAAHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL3299072 | 0.76 | KDM4E (0.45) | GAAHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL13298024 | 0.75 | DYRK1A (0.36) | GAAHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL13298034 | 0.73 | CCR1 (0.45) | KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL13298076 | 0.73 | LMNA (0.33) | FYN | |
| SCHEMBL13317045 | 0.73 | KDM4E (0.40) | HPGDKDM4EMAPT | |
| SCHEMBL1396125 | 0.72 | FYN (0.36) | GAAHPGDKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741318-B2 | Pyrazolo [1,5-A]pyrimidine adenosine A2a receptor antagonists | SCHERING CORPORATION (US) | 2010-06-22 | — | — | US | disclosed |