Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | AAK1 | Q2M2I8 | 8/20 | 0.47 |
| ▸ | TERT | O14746 | 3/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13815091 | 0.96 | AAK1 (0.48) | SUV39H2LTA4HAAK1TERTCHEK1 | |
| SCHEMBL13815084 | 0.91 | SUV39H2 (0.51) | SUV39H2LTA4HAAK1TERTCHEK1 | |
| SCHEMBL13815099 | 0.87 | AAK1 (0.48) | SUV39H2LTA4HAAK1TERTCHEK1 | |
| SCHEMBL15317940 | 0.84 | ERAP2 (0.48) | SUV39H2LTA4HAAK1TERTMMP2 | |
| SCHEMBL13815093 | 0.84 | AAK1 (0.43) | AAK1CHEK1ROCK2ROCK1 | |
| SCHEMBL12766953 | 0.83 | ERAP2 (0.47) | SUV39H2LTA4HAAK1TERTMMP2 | |
| SCHEMBL19445695 | 0.83 | SUV39H2 (0.45) | SUV39H2LTA4HAAK1TERTCHEK1 | |
| SCHEMBL13962658 | 0.83 | ERAP2 (0.47) | SUV39H2LTA4HAAK1TERTMMP2 | |
| SCHEMBL19445813 | 0.82 | ERAP2 (0.47) | SUV39H2LTA4HAAK1TERTMMP2 | |
| Delparantag SCHEMBL10267622 | 0.82 | ERAP2 (0.47) | SUV39H2LTA4HAAK1TERTMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745662-B2 | Polycationic compounds and uses thereof | POLYMEDIX, INC. (US) | 2010-06-29 | — | — | US | disclosed |
| US-7553876-B2 | Polycationic compounds and uses thereof | POLYMEDIX, INC. (US) | 2009-06-30 | — | — | US | disclosed |