Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23646039 | 0.77 | NAALAD2 (0.40) | NAALAD2GRM1CYP1A2GRIA1GRIA2 | |
| SCHEMBL31326721 | 0.75 | NAALAD2 (0.44) | NAALAD2GRM1CYP1A2ALDH1A1RECQL | |
| SCHEMBL353803 | 0.69 | NAALAD2 (0.39) | NAALAD2GRM1CYP1A2KDM6BKDM4A | |
| SCHEMBL23796262 | 0.67 | NAALAD2 (0.47) | NAALAD2CYP1A2ALDH1A1RECQLPIN1 | |
| SCHEMBL31696740 | 0.64 | NAALAD2 (0.60) | NAALAD2GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL24251553 | 0.64 | NAALAD2 (0.60) | NAALAD2GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL28428255 | 0.61 | ALDH1A1 (0.36) | GRM1CYP1A2ALDH1A1LMNAGRM5 | |
| SCHEMBL20652615 | 0.61 | NAALAD2 (0.39) | NAALAD2CYP1A2KDM6BKDM4AKDM5A | |
| SCHEMBL30832993 | 0.58 | CYP3A4 (0.37) | GRM1CYP1A2LMNAGRM5KDM4E | |
| SCHEMBL16509726 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144868-A1 | Novel Neuroprotective Compounds and Uses Thereof | RAMOT AT AVIV UNIVERSITY LTD. (IL) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144868-A1 | Novel Neuroprotective Compounds and Uses Thereof | GRM2, GRIN1, GRM3 | NAALAD2 1720/4885GRM1 5/4885CYP1A2 2633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.