Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 5/20 | 1.00 |
| ▸ | GRIA3 | P42263 | 5/20 | 1.00 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.59 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.49 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.49 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.49 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17596528 | 0.85 | GRIA1 (0.74) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| SCHEMBL8812980 | 0.83 | GRIA1 (0.71) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| SCHEMBL8812978 | 0.83 | GRIA1 (0.71) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| (S)-Ampa SCHEMBL667915 | 0.82 | GRIA1 (0.69) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| (R,S)-Ampa SCHEMBL68799 | 0.82 | GRIA1 (0.69) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| (R,S)-Ampa SCHEMBL2458874 | 0.82 | GRIA1 (0.69) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| (R,S)-Ampa SCHEMBL7200264 | 0.81 | GRIA1 (0.68) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| (R,S)-Ampa SCHEMBL7200262 | 0.81 | GRIA1 (0.68) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| SCHEMBL7167715 | 0.77 | GRIA1 (0.71) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| SCHEMBL7167719 | 0.77 | GRIA1 (0.71) | GRIA1GRIA3GRIA2GRIA4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144868-A1 | Novel Neuroprotective Compounds and Uses Thereof | RAMOT AT AVIV UNIVERSITY LTD. (IL) | 2010-06-10 | — | — | US | disclosed |
| US-20100144868-A1 | Novel Neuroprotective Compounds and Uses Thereof | RAMOT AT AVIV UNIVERSITY LTD. (IL) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144868-A1 | Novel Neuroprotective Compounds and Uses Thereof | GRM2, GRIN1, GRM3 | GRIA1 22/4885GRIA3 18/4885GRIA2 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.