Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 5/20 | 0.69 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.69 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.61 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.50 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.50 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.50 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (R,S)-Ampa SCHEMBL2458874 | 1.00 | GRIA1 (0.69) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| (S)-Ampa SCHEMBL667915 | 1.00 | GRIA1 (0.69) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| (R,S)-Ampa SCHEMBL7200264 | 0.98 | GRIA1 (0.68) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| (R,S)-Ampa SCHEMBL7200262 | 0.98 | GRIA1 (0.68) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| (R,S)-Ampa SCHEMBL23242452 | 0.90 | GRIA1 (0.58) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| (R,S)-Ampa SCHEMBL19086372 | 0.90 | GRIA1 (0.58) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| (R,S)-Ampa SCHEMBL6553747 | 0.88 | GRIA1 (0.56) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| (S)-Ampa SCHEMBL28091565 | 0.85 | GRIA1 (0.53) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| SCHEMBL8812980 | 0.85 | GRIA1 (0.71) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| SCHEMBL8812978 | 0.85 | GRIA1 (0.71) | GRIA1GRIA3GRIA2GRIA4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4708 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250250354-A1 | NEW CLASS OF MOLECULES FOR SELECTIVE CLEARANCE OF ANTIBODY | OSE IMMUNOTHERAPEUTICS (FR) | 2025-08-07 | — | — | US | claimed |
| US-20250213564-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND OTHER NEUROGENERATIVE DISEASE | THE RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC. | 2025-07-03 | — | — | US | claimed |
| EP-4577305-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND OTHER NEUROGENERATIVE DISEASE | 1/1THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-07-02 | — | — | EP | claimed |
| CN-119881321-A | Application of AMPAR protein group in response to terahertz waves | 中国人民解放军军事科学院军事医学研究院 | 2025-04-25 | — | — | CN | claimed |
| EP-4508074-A1 | NEW CLASS OF MOLECULES FOR SELECTIVE CLEARANCE OF ANTIBODY | OSE IMMUNOTHERAPEUTICS (FR) | 2025-02-19 | — | — | EP | claimed |
| CN-119487066-A | Targeted protein degradation system and application thereof | 羿尊生物医药（浙江）有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-119233999-A | Fusion protein of targeting cell membrane receptor protein and application thereof | 羿尊生物医药（浙江）有限公司 | 2024-12-31 | — | — | CN | claimed |
| EP-4463138-A1 | MULTI-VESICULAR LIPID NANOPARTICLE TOLEROGENIC VACCINES FOR INDUCTION OF SYSTEMIC IMMUNE TOLERANCE IN VIVO | Karma Biotechnologies (US) | 2024-11-20 | — | — | EP | claimed |
| WO-2023137227-A9 | MULTI-VESICULAR LIPID NANOPARTICLE TOLEROGENIC VACCINES FOR INDUCTION OF SYSTEMIC IMMUNE TOLERANCE IN VIVO | KARMA BIOTECHNOLOGIES (US) | 2024-07-11 | — | — | WO | claimed |
| EP-4392438-A2 | FLUORESCENT SENSOR FOR MONITORING CALCIUM DYNAMICS | Yang, Jenny (US) | 2024-07-03 | — | — | EP | claimed |
| EP-0918518-A1 | TREATMENT OF MOOD/AFFECTIVE DISORDERS BY GLUTAMATERGIC UPMODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-06-02 | — | — | EP | claimed |
| WO-1999021422-A1 | TREATMENT OF SCHIZOPHRENIA WITH AMPAKINES AND NEUROLEPTICS | CORTEX PHARMACEUTICALS, INC. (US) | 1999-05-06 | — | — | WO | claimed |
| EP-0859763-A1 | DIHYDROPHTHALAZINE ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS | Bearsden Bio, Inc. (US) | 1998-08-26 | — | — | EP | claimed |
| US-5716956-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | BEARSDEN BEARSDEN BIO, INC. (US) | 1998-02-10 | — | — | US | claimed |
| WO-1997039750-A1 | TREATMENT OF MOOD/AFFECTIVE DISORDERS BY GLUTAMATERGIC UPMODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-10-30 | — | — | WO | claimed |
| WO-1997026247-A1 | 1-ARYLPHTHALAZINE ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS | SYMPHONY PHARMACEUTICALS, INC. (US) | 1997-07-24 | — | — | WO | claimed |
| WO-1996040646-A1 | DIHYDROPHTHALAZINE ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS | SYMPHONY PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | claimed |
| US-5202257-A | Pure DNA which is capable of hybridizing with receptor polynucleotides under mild conditions | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1993-04-13 | — | — | US | claimed |
| EP-0497884-A1 | GLUTAMATE RECEPTOR COMPOSITIONS AND METHODS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-08-12 | — | — | EP | claimed |
| WO-1991006648-A1 | GLUTAMATE RECEPTOR COMPOSITIONS AND METHODS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1991-05-16 | — | — | WO | claimed |