Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12864544 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MAPTPOLBHTTTP53 | |
| SCHEMBL13319979 | 0.90 | ALDH1A1 (0.52) | ALDH1A1MAPTPOLBHTTTP53 | |
| SCHEMBL12864543 | 0.85 | ALDH1A1 (0.52) | ALDH1A1MAPTPOLBHTTTP53 | |
| SCHEMBL1171793 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPTPOLBHTTTP53 | |
| SCHEMBL13319967 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPTPOLBHTTTP53 | |
| SCHEMBL13319978 | 0.81 | KDM1A (0.43) | ALDH1A1MAPTPOLBHTTTP53 | |
| SCHEMBL12864541 | 0.81 | KDM1A (0.43) | ALDH1A1MAPTPOLBHTTTP53 | |
| SCHEMBL12864540 | 0.79 | CYP3A4 (0.36) | ALDH1A1MAPTPOLBHTTTP53 | |
| SCHEMBL22143046 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTPOLBHTTTP53 | |
| SCHEMBL12864009 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MAPTPOLBHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120740-A1 | PRODRUGS OF FUSED HETEROCYCLIC INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACOR INC. (US) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120740-A1 | PRODRUGS OF FUSED HETEROCYCLIC INHIBITORS OF D-AMINO ACID OXIDASE | DDO, DAO, AOC1 | ALDH1A1 350/4885MAPT 2275/4885POLB 2437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.