SCHEMBL1332008

SCHEMBL1332008

O=S(=O)(c1ccccc1)c1cc(S(=O)(=O)c2ccccc2)cc(S(=O)(=O)c2ccccc2)c1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 4/20 0.82
ALDH1A1 P00352 4/20 0.53
TSHR P16473 2/20 0.53
LMNA P02545 2/20 0.53
THRB P10828 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.52
POLB P06746 2/20 0.52
MAPT P10636 1/20 0.52
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CA12 O43570 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
PLA2G7 Q13093 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28709181 0.92 HTR6 (0.78) HTR6ALDH1A1TSHRLMNATHRB
SCHEMBL9140147 0.92 HTR6 (0.78) HTR6ALDH1A1TSHRLMNATHRB
(Phenylsulfonyl)Benzene SCHEMBL28730795 0.91 HTR6 (0.88) HTR6ALDH1A1TSHRLMNATHRB
(Phenylsulfonyl)Benzene SCHEMBL29775288 0.91 HTR6 (1.00) HTR6ALDH1A1TSHRSMN1; SMN2POLB
(Phenylsulfonyl)Benzene SCHEMBL13735236 0.91 HTR6 (1.00) HTR6ALDH1A1TSHRSMN1; SMN2POLB
(Phenylsulfonyl)Benzene SCHEMBL29473549 0.91 HTR6 (1.00) HTR6ALDH1A1TSHRSMN1; SMN2POLB
(Phenylsulfonyl)Benzene SCHEMBL29450723 0.91 HTR6 (1.00) HTR6ALDH1A1TSHRSMN1; SMN2POLB
(Phenylsulfonyl)Benzene SCHEMBL30255 0.91 HTR6 (1.00) HTR6ALDH1A1TSHRSMN1; SMN2POLB
(Phenylsulfonyl)Benzene SCHEMBL28119187 0.91 HTR6 (1.00) HTR6ALDH1A1TSHRSMN1; SMN2POLB
SCHEMBL18503833 0.88 HTR6 (0.64) HTR6ALDH1A1TSHRLMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304508-B2 Fluorine-containing dicarboxylic acids and their novel polymer compounds CENTRAL GLASS COMPANY, LIMITED (JP) 2012-11-06 US disclosed
US-20110282026-A1 Fluorine-Containing Dicarboxylic Acids and Their Novel Polymer Compounds CENTRAL GLASS COMPANY, LIMITED (JP) 2011-11-17 US disclosed
US-8003749-B2 Fluorine-containing dicarboxylic acids and their novel polymer compounds CENTRAL GLASS COMPANY, LIMITED (JP) 2011-08-23 US disclosed
US-20090030173-A1 NOVEL FLUORINE-CONTAINING DICARBOXYLIC ACIDS AND THEIR NOVEL POLYMER COMPOUNDS CENTRAL GLASS COMPANY, LIMITED (JP) 2009-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090030173-A1 NOVEL FLUORINE-CONTAINING DICARBOXYLIC ACIDS AND THEIR NOVEL POLYMER COMPOUNDS AFF1, ODC1, DDC HTR6 4785/4885ALDH1A1 527/4885TSHR 3942/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.