SCHEMBL13320186

SCHEMBL13320186

CCn1c2ccc(C(=O)O)cc2c2cc(C(=O)CC(C)=O)ccc21

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.53
ALDH1A1 P00352 4/20 0.53
KDM4E B2RXH2 8/20 0.52
HTT P42858 2/20 0.52
TSHR P16473 2/20 0.50
HSD17B10 Q99714 2/20 0.50
MAPT P10636 4/20 0.49
KMT2A Q03164 3/20 0.47
LMNA P02545 1/20 0.47
PTGER4 P35408 4/20 0.46
NPSR1 Q6W5P4 1/20 0.46
RAB9A P51151 2/20 0.44
MEN1 O00255 2/20 0.44
THRB P10828 1/20 0.44
GAA P10253 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
HCAR3 P49019 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29629313 0.88 HPGD (0.65) HPGDALDH1A1KDM4EHTTTSHR
SCHEMBL8922345 0.88 HPGD (0.65) HPGDALDH1A1KDM4EHTTTSHR
SCHEMBL29629312 0.88 HPGD (0.65) HPGDALDH1A1KDM4EHTTTSHR
Hydrochloric Acid SCHEMBL8920877 0.86 HPGD (0.63) HPGDALDH1A1KDM4EHTTTSHR
SCHEMBL13320187 0.86 KDM4E (0.50) HPGDALDH1A1KDM4EHTTTSHR
SCHEMBL13320199 0.84 KDM4E (0.48) HPGDALDH1A1KDM4EHTTTSHR
SCHEMBL13351986 0.83 RORC (0.50) HPGDALDH1A1KDM4EHTTTSHR
SCHEMBL9747639 0.82 PTGER4 (0.59) HPGDALDH1A1KDM4EHTTTSHR
SCHEMBL2734561 0.81 ALDH1A1 (0.78) HPGDALDH1A1KDM4EHTTHSD17B10
SCHEMBL28267725 0.81 KDM4E (0.63) HPGDALDH1A1KDM4EHTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338081-B2 Alkali-developable photosensitive resin composition and β-diketone compound ADEKA CORPORATION (JP) 2012-12-25 US disclosed
US-8338081-B2 Alkali-developable photosensitive resin composition and β-diketone compound ADEKA CORPORATION (JP) 2012-12-25 US disclosed
US-20100129753-A1 ALKALI-DEVELOPABLE PHOTOSENSITIVE RESIN COMPOSITION AND BETA-DIKETONE COMPOUND ADEKA CORPORATION (JP) 2010-05-27 US disclosed
US-20100129753-A1 ALKALI-DEVELOPABLE PHOTOSENSITIVE RESIN COMPOSITION AND BETA-DIKETONE COMPOUND ADEKA CORPORATION (JP) 2010-05-27 US disclosed
EP-2175320-A1 ALKALI-DEVELOPABLE PHOTOSENSITIVE RESIN COMPOSITION AND -DIKETONE COMPOUND Adeka Corporation (JP) 2010-04-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100129753-A1 ALKALI-DEVELOPABLE PHOTOSENSITIVE RESIN COMPOSITION AND BETA-DIKETONE COMPOUND RPS14, ACAD11, OR10J3 HPGD 2227/4885ALDH1A1 1770/4885KDM4E 1572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.