Sugi Predict

Sugi Predict / Compounds / SCHEMBL1332019

SCHEMBL1332019

SCHEMBL1332019

CCCCCCCCCCCCNCCCS(=O)(=O)O

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.56
▸ TSHR P16473 1/20 0.56
▸ CA1 P00915 2/20 0.53
▸ CA2 P00918 2/20 0.53
▸ EPHX2 P34913 1/20 0.53
▸ S1PR2 O95136 5/20 0.52
▸ S1PR4 O95977 5/20 0.52
▸ S1PR1 P21453 5/20 0.52
▸ S1PR3 Q99500 5/20 0.52
▸ S1PR5 Q9H228 1/20 0.52
▸ RELA Q04206 4/20 0.50
▸ PPARA Q07869 2/20 0.47
▸ EPHX1 P07099 4/20 0.46
▸ ADH1B P00325 1/20 0.46
▸ ADH1C P00326 1/20 0.46
▸ ADH1A P07327 1/20 0.46
▸ ADH4 P08319 1/20 0.46
▸ ADH7 P40394 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL917055 1.00 ALDH1A1 (0.56) ALDH1A1TSHRCA1CA2EPHX2
SCHEMBL917570 1.00 ALDH1A1 (0.56) ALDH1A1TSHRCA1CA2EPHX2
SCHEMBL918031 1.00 ALDH1A1 (0.56) ALDH1A1TSHRCA1CA2EPHX2
SCHEMBL917576 1.00 ALDH1A1 (0.56) ALDH1A1TSHRCA1CA2EPHX2
SCHEMBL917965 1.00 ALDH1A1 (0.56) ALDH1A1TSHRCA1CA2EPHX2
SCHEMBL917918 1.00 ALDH1A1 (0.56) ALDH1A1TSHRCA1CA2EPHX2
SCHEMBL917335 1.00 ALDH1A1 (0.56) ALDH1A1TSHRCA1CA2EPHX2
SCHEMBL918208 1.00 ALDH1A1 (0.56) ALDH1A1TSHRCA1CA2EPHX2
SCHEMBL918549 1.00 ALDH1A1 (0.56) ALDH1A1TSHRCA1CA2EPHX2
SCHEMBL918712 1.00 ALDH1A1 (0.56) ALDH1A1TSHRCA1CA2EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2916820-B1 DELIVERY OF BIOLOGICALLY-ACTIVE AGENTS USING VOLATILE, HYDROPHOBIC SOLVENTS ROCHAL TECH LLC (US) 2023-10-11 — — EP claimed
CN-114763503-B Stretching lubricating liquid for metal products and preparation method thereof 东莞市登喜达表面处理科技有限公司 2023-05-23 — — CN claimed
CN-114763503-A Stretching lubricating liquid for metal products and preparation method thereof 东莞市登喜达表面处理科技有限公司 2022-07-19 — — CN claimed
CN-112120042-A Hypochlorous acid disinfectant with efficient sterilization function and preparation method thereof 山东众之康生物科技有限公司 2020-12-25 — — CN claimed
CN-109810974-B Reagent composition for extracting HIV-1 nucleic acid and method thereof 珠海丽珠试剂股份有限公司 2020-11-24 — — CN claimed
CN-109422887-A A kind of anionic starch microballoon and its preparation method and application 中国石油化工股份有限公司 2019-03-05 — — CN claimed
CN-109423264-A A kind of spherex and its preparation method and application 中国石油化工股份有限公司 2019-03-05 — — CN claimed
CN-109422851-A A kind of cationic starch microballoon and its preparation method and application 中国石油化工股份有限公司 2019-03-05 — — CN claimed
EP-1799308-B1 CONDITIONING SHAMPOOS WITH DETERGENT SOLUBLE SILICONES COLGATE PALMOLIVE CO (US) 2014-06-04 — — EP claimed
US-20110281951-A1 Compositions and methods for treating amyloidosis BHI LIMITED PARTNERSHIP (CA) 2011-11-17 — — US claimed
EP-1276483-B1 COMPOSITIONS AND METHODS FOR TREATING AMYLOIDOSIS USING SULPHONATE DERIVATIVES BELLUS HEALTH INT LTD (CH) 2009-09-02 — — EP claimed
US-20090099100-A1 Compositions and methods for treating amyloidosis BELLUS HEALTH (INTERNATIONAL) LIMITED (CH) 2009-04-16 — — US claimed
US-20050048000-A1 Amyloid targeting imaging agents and uses thereof NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2005-03-03 — — US claimed
EP-0915693-B1 AN OIL-IN-WATER EMULSION FOR USE ON HUMAN SKIN FOR CLEANSING, PRESERVING OR IMPROVING THE CONDITION OF THE SKIN PLUM KEMI PRODUKTION AS (DK) 2003-10-01 — — EP claimed
JP-2003517458-A — — 2003-05-27 — — JP claimed
EP-1303311-A2 AMYLOID TARGETING IMAGING AGENTS AND USES THEREOF Neurochem, Inc. (CA) 2003-04-23 — — EP claimed
EP-1276483-A2 COMPOSITIONS AND METHODS FOR TREATING AMYLOIDOSIS USING SULPHONATE DERIVATIVES QUEEN'S UNIVERSITY AT KINGSTON (CA) 2003-01-22 — — EP claimed
US-20020115717-A1 Amyloid targeting imaging agents and uses thereof NEUROCHEM (INTERNATIONAL) LIMITED (GI) 2002-08-22 — — US claimed
WO-2002007781-A2 AMYLOID TARGETING IMAGING AGENTS AND USES THEREOF NEUROCHEM INC. (CA) 2002-01-31 — — WO claimed
WO-2000064420-A2 COMPOSITIONS AND METHODS FOR TREATING AMYLOIDOSIS USING SULPHONATE DERIVATIVES QUEEN'S UNIVERSITY AT KINGSTON (CA) 2000-11-02 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090099100-A1 Compositions and methods for treating amyloidosis TTR, SNCA, ARSA ALDH1A1 1526/4885TSHR 1739/4885CA1 326/4885
US-20110281951-A1 Compositions and methods for treating amyloidosis TTR, SNCA, ARSA ALDH1A1 1526/4885TSHR 1739/4885CA1 326/4885
US-20050048000-A1 Amyloid targeting imaging agents and uses thereof APP, APBA1, BACE1 ALDH1A1 3305/4885TSHR 4314/4885CA1 720/4885
US-20020115717-A1 Amyloid targeting imaging agents and uses thereof APP, APBA1, BACE1 ALDH1A1 3305/4885TSHR 4314/4885CA1 720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.