Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | BAZ2B | Q9UIF8 | 11/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CASP1 | P29466 | 3/20 | 0.51 |
| ▸ | CASP7 | P55210 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2832897 | 0.92 | LMNA (0.76) | LMNAPABPC1ATMSMN1; SMN2BAZ2B | |
| SCHEMBL31117423 | 0.86 | LMNA (0.64) | LMNAPABPC1ATMSMN1; SMN2BAZ2B | |
| SCHEMBL10127719 | 0.86 | LMNA (0.66) | LMNAPABPC1ATMSMN1; SMN2BAZ2B | |
| SCHEMBL30228387 | 0.86 | TRPV1 (0.59) | LMNAPABPC1ATMSMN1; SMN2BAZ2B | |
| SCHEMBL5104575 | 0.85 | BAZ2B (0.71) | LMNAPABPC1ATMSMN1; SMN2BAZ2B | |
| SCHEMBL16140457 | 0.85 | BAZ2B (0.71) | LMNAPABPC1ATMSMN1; SMN2BAZ2B | |
| SCHEMBL21114757 | 0.85 | BAZ2B (0.71) | LMNAPABPC1ATMSMN1; SMN2BAZ2B | |
| SCHEMBL409534 | 0.85 | BAZ2B (0.71) | LMNAPABPC1ATMSMN1; SMN2BAZ2B | |
| SCHEMBL3312381 | 0.84 | LMNA (0.57) | LMNAPABPC1ATMSMN1; SMN2BAZ2B | |
| SCHEMBL21162488 | 0.84 | BAZ2B (0.74) | LMNAPABPC1ATMSMN1; SMN2BAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100125085-A1 | PYRIDOINDOLE MODULATORS OF NMDA RECEPTOR AND ACETYLCHOLINESTERASE | AUSPEX PHARMACEUTICALS, INC. (US) | 2010-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100125085-A1 | PYRIDOINDOLE MODULATORS OF NMDA RECEPTOR AND ACETYLCHOLINESTERASE | GRIN3A, GRIK5, CHRNA5 | LMNA 3662/4885PABPC1 4237/4885ATM 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.